PMID: 8951940Oct 1, 1996Paper

Epidural and subcutaneous morphine in the management of cancer pain: a double-blind cross-over study

Pain
E KalsoA Vainio

Abstract

Ten patients who suffered from severe cancer-related pain participated in a randomised, double-blind and cross-over study to compare the effectiveness and acceptability of epidural and subcutaneous administration of morphine. The patients titrated themselves pain-free in 48 h using a patient controlled analgesia system. The median daily doses calculated from the consumption of the last 4-h study period were 372 mg for subcutaneous and 106 mg for epidural administration. The two modes of morphine administration turned out to be comparable in terms of both effectiveness and acceptability. Both treatments provided better pain relief with less adverse effects compared with the prestudy oral morphine treatment.

References

Jun 9, 1979·British Medical Journal·P S Russell
Feb 11, 1990·Journal of Pain and Symptom Management·P StoreyE E Tarver
May 1, 1990·Clinical Pharmacology and Therapeutics·E Kalso, A Vainio
Sep 1, 1990·Clinical Pharmacology and Therapeutics·H J McQuayR A Moore
Jan 1, 1985·Acta Anaesthesiologica Scandinavica·S Arnér, B Arnér
Apr 1, 1988·Acta Anaesthesiologica Scandinavica·A Vainio, I Tigerstedt
Jan 16, 1982·Lancet·R J Dickson, P S Russell
Nov 1, 1981·Clinical Pharmacology and Therapeutics·J SäweA Rane

❮ Previous
Next ❯

Citations

Nov 28, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jeff MyersCindy Walker-Dilks
Jun 16, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Eduardo Bruera, David Hui
Dec 12, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Sebastiano Mercadante, Patrizia Giardina
Jul 7, 1999·Lancet·H McQuay
Feb 28, 2001·Journal of Pain and Symptom Management·S Mercadante, R K Portenoy
Apr 20, 2001·Journal of Pain and Symptom Management·S Mercadante, R K Portenoy
Jun 5, 2003·Journal of Pain and Symptom Management·Franco De ConnoCarla Ripamonti
Aug 26, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S Mercadante
Oct 20, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C I RipamontiUNKNOWN ESMO Guidelines Working Group
Aug 24, 2011·Experimental Diabetes Research·Ana Eliza AndreazziPaulo Cezar de Freitas Mathias
Mar 25, 2008·Therapeutics and Clinical Risk Management·Mario MandalàSandro Barni
Feb 5, 2002·Clinical Pharmacokinetics·Jorn LotschGerd Geisslinger
Jul 4, 2001·Drugs·C Ripamonti, E D Dickerson
Aug 5, 2008·American Journal of Veterinary Research·Bruno H PypendopJan E Ilkiw
Apr 23, 2011·Parkinson's Disease·Verónica Muñoz-Soriano, Nuria Paricio
May 13, 2014·Drugs & Aging·Sophie PautexGilbert B Zulian
Sep 11, 2013·Journal of Pain and Symptom Management·Katrin Ruth SigurdardottirDagny Faksvåg Haugen
Feb 4, 2009·Critical Reviews in Oncology/hematology·Carla Ripamonti, Elena Bandieri
Nov 11, 2008·La Presse médicale·Antoine RobeletBrigitte Sabatier
Dec 7, 2007·Anesthesiology Clinics·John D Markman, Annie Philip
Feb 27, 2007·The Medical Clinics of North America·John D Markman, Annie Philip
Sep 1, 2005·The Lancet Oncology·Mellar P DavisSusan B LeGrand
Mar 2, 2005·European Journal of Pain : EJP·Eija Kalso
Aug 19, 2008·European Journal of Pain : EJP·Andrew N DaviesUNKNOWN Science Committee of the Association for Palliative Medicine of Great Britain and Ireland
Feb 17, 2015·Acta Anaesthesiologica Scandinavica·G P KuritaUNKNOWN European Palliative Care Research Collaborative (EPCRC)
Jun 2, 2012·Journal of Pain and Symptom Management·Akhila ReddyEduardo Bruera
Sep 22, 2000·Current Review of Pain·C Ripamonti, F Fulfaro
Jul 28, 2016·European Journal of Internal Medicine·Sebastiano Mercadante
May 4, 2004·The Annals of Pharmacotherapy·Stacey L Anderson, Scott T Shreve
Jul 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Carla Ripamonti, Cinzia Brunelli
Feb 15, 2007·The Annals of Pharmacotherapy·Asad E PatanwalaBrian L Erstad
Jun 1, 2005·Palliative Medicine·Caroline Fonzo-ChristePascal Bonnabry
Oct 31, 2002·Palliative Medicine·P Good, B Stafford
Oct 19, 2007·Palliative Medicine·Paul W KeeleySimon I R Noble
Jun 29, 2011·Palliative Medicine·Geana Paula KuritaUNKNOWN European Palliative Care Research Collaborative (EPCRC)
Aug 25, 2017·BMJ Supportive & Palliative Care·Andrew Neil DaviesBernadette Lee
Aug 16, 2011·British Journal of Nursing : BJN·Andrew N Davies
Sep 25, 2002·International Journal of Palliative Nursing·K TinnellyK Cousins
Mar 7, 2019·Neuromodulation : Journal of the International Neuromodulation Society·David Daewhan KimNabil Sibai
Dec 29, 1998·The American Journal of Hospice & Palliative Care·S G Mercadante
Apr 23, 2016·The Cochrane Database of Systematic Reviews·Philip J WiffenR Andrew Moore
May 25, 2005·The American Journal of Hospice & Palliative Care·Luiz Guilherme L Soares

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Mellar P DavisSusan B LeGrand
Journal of Pain and Symptom Management
S MercadanteS Pumo
© 2021 Meta ULC. All rights reserved