Epidural versus non-epidural or no analgesia for pain management in labour.

The Cochrane Database of Systematic Reviews
M Anim-SomuahAnna Cuthbert

Abstract

Epidural analgesia is a central nerve block technique achieved by injection of a local anaesthetic close to the nerves that transmit pain, and is widely used as a form of pain relief in labour. However, there are concerns about unintended adverse effects on the mother and infant. This is an update of an existing Cochrane Review (Epidural versus non-epidural or no analgesia in labour), last published in 2011. To assess the effectiveness and safety of all types of epidural analgesia, including combined-spinal-epidural (CSE) on the mother and the baby, when compared with non-epidural or no pain relief during labour. We searched Cochrane Pregnancy and Childbirth's Trials Register (ClinicalTrials.gov), the WHO International Clinical Trials Registry Platform (ICTRP) (30 April 2017), and reference lists of retrieved studies. Randomised controlled trials comparing all types of epidural with any form of pain relief not involving regional blockade, or no pain relief in labour. We have not included cluster-randomised or quasi-randomised trials in this update. Two review authors independently assessed trials for inclusion and risks of bias, extracted data and checked them for accuracy. We assessed selected outcomes using the GRADE approach...Continue Reading

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Citations

Jun 6, 2018·The Cochrane Database of Systematic Reviews·Lesley A SmithAnna Cuthbert
Nov 10, 2018·The Cochrane Database of Systematic Reviews·Kate F WalkerNia W Jones
Jan 10, 2019·Minerva anestesiologica·Bigna S BuddebergThierry Girard
Jul 25, 2019·Cadernos de saúde pública·Maria do Carmo LealMaria Esther de Albuquerque Vilela
Feb 8, 2020·The Cochrane Database of Systematic Reviews·Caroline A SmithBita Mesgarpour
Mar 11, 2020·Minerva anestesiologica·Massimiliano CarassitiEmiliano Schena
May 24, 2019·The Journal of Perinatal Education·Judith A Lothian
Apr 3, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Alessandro FavilliSandro Gerli
Aug 6, 2020·Anesthesiology and Pain Medicine·Fariba AlmassinokianiFatemeh Sharifzadeh
Oct 1, 2020·International Journal of Environmental Research and Public Health·I-Shiang TzengKuo-Hu Chen
Oct 28, 2020·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Dolores M McKeenUNKNOWN Canadian Anesthesiologists’ Society
Jan 7, 2021·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Allana MunroNatalie O Rosen
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May 1, 2021·International Journal of Environmental Research and Public Health·Xavier Espada-TrespalaciosRamon Escuriet
May 14, 2021·Expert Review of Clinical Pharmacology·Xiaojun ChenJin Yu
Aug 26, 2020·Scandinavian Journal of Pain·Ellen BlixTine Schauer Eri
Sep 30, 2021·International Urogynecology Journal·Mafalda S CardosoTeresa Rodrigues
Jul 7, 2021·Scientific Reports·Louise LundborgMia Ahlberg

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