Epigenetic analysis of kinetochore assembly on variant human centromeres

Trends in Genetics : TIG
P E Warburton

Abstract

Human centromere formation involves the assembly of the mitotic kinetochore onto chromosomal locations that contain the interphase prekinetochore. Immunofluorescent analysis of two functionally converse human centromere variants, neocentromeres and inactive centromeres, has been used to evaluate the functional significance of over 24 CENTROMERE proteins, providing important insight into the epigenetics of centromere formation and kinetochore assembly.

References

Apr 1, 1997·Trends in Genetics : TIG·D Kipling, P E Warburton
May 21, 1998·Nature Biotechnology·M IkenoH Masumoto
Aug 12, 1998·The Journal of Cell Biology·T ManeyL Wordeman
Nov 7, 1998·Nature Genetics·B A Sullivan, H F Willard
May 14, 1999·Current Opinion in Genetics & Development·K W DobieG H Karpen
Dec 23, 1999·Human Molecular Genetics·E EarleK H Choo
Jan 5, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·A A Van HooserB R Brinkley
Jan 19, 2000·Nature·B D Strahl, C D Allis
Apr 8, 2000·Trends in Cell Biology·K H Choo
Sep 28, 2000·Chromosoma·G GimelliD He

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Citations

Apr 5, 2011·Cellular and Molecular Life Sciences : CMLS·Fumiaki UchiumiSei-ichi Tanuma
Jul 25, 2012·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Jan H BergmannWilliam C Earnshaw
Apr 23, 2003·Experimental Cell Research·Ilia I OuspenskiB R Brinkley
Jun 5, 2002·Trends in Genetics : TIG·Zoia Larin, José E Mejía
May 7, 2013·Nature Structural & Molecular Biology·Dan HassonBen E Black
Dec 4, 2002·The Journal of Cell Biology·Jun-ichirou OhzekiHiroshi Masumoto
Jan 28, 2005·Molecular Biology of the Cell·Nathaniel S Edwards, Andrew W Murray
Oct 18, 2007·Molecular Biology and Evolution·Claudio CasolaCédric Feschotte
Feb 1, 2003·Nucleic Acids Research·Ute PreussKarl Heinz Scheidtmann
Aug 29, 2006·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Ryan HeitMichael J Hendzel
May 9, 2013·Cellular and Molecular Life Sciences : CMLS·Chiara VardabassoEmily Bernstein
Mar 14, 2014·Nucleic Acids Research·Mekonnen Lemma DechassaKarolin Luger
Aug 11, 2004·The Journal of Cell Biology·Mounia GuenatriGeneviève Almouzni
Nov 20, 2002·American Journal of Medical Genetics·Juliana Godoy AssumpçãoPeter E Warburton
Apr 12, 2008·Journal of Cellular Biochemistry·Randall S GieniMichael J Hendzel
Sep 11, 2004·Biochemical and Biophysical Research Communications·Motonobu KatohMitsuo Oshimura
May 29, 2002·Gene Therapy·B R GrimesC J Farr
Jan 30, 2020·Cell Cycle·M Lienhard SchmitzMarkus Seibert
Apr 29, 2015·Biomolecular Concepts·Roy Blum
Jul 13, 2002·American Journal of Medical Genetics·Shulan LiPeter E Warburton
Jul 9, 2017·Chromosoma·Oscar MolinaWilliam C Earnshaw
Sep 4, 2003·Journal of Cell Science·Megumi NakanoHiroshi Masumoto
Oct 6, 2001·Science·M G SchuelerH F Willard

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