Epigenetic ON/OFF Switches for Obesity

Cell
Carmelo QuartaMatthias H Tschöp

Abstract

Heritable epigenetic mechanisms might contribute to the worldwide increase in the prevalence of obesity. Dalgaard et al. identify an epigenetic molecular switch that controls body weight control. The discovery suggests the existence of mammalian polyphenism in energy metabolism and might have implications for strategies to limit the obesity epidemic.

References

Mar 19, 2014·Lancet·Katherine J DickNilesh J Samani
Jan 30, 2016·Cell·Kevin DalgaardJ Andrew Pospisilik

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Citations

Apr 8, 2017·Scandinavian Journal of Public Health·Rejane Augusta de Oliveira FigueiredoElisabete Weiderpass
Mar 23, 2018·Human Molecular Genetics·Luz D OrozcoMatteo Pellegrini
Sep 17, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Ruifan Wu, Xinxia Wang
Aug 31, 2017·Current Atherosclerosis Reports·Sonsoles MorcilloFrancisco J Tinahones
Mar 1, 2019·Nature Reviews. Endocrinology·Matthias Blüher
Jun 30, 2021·Critical Reviews in Biochemistry and Molecular Biology·Kalhara R MenikdiwelaNaima Moustaid-Moussa

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