Epigenetics of solid cancer stem cells

Methods in Molecular Biology
Alok Mishra, Mukesh Verma

Abstract

Epigenetics is an emerging science that can help to explain carcinogenesis. The possibility that carcinogenesis may originate in a stem cell process was proposed recently. Stem cells are generated and contribute to tumor formation during the process of tumor development. This chapter focuses on the role of epigenetics and genetics in stem cell formation, different theories about the origin of cancer stem cells (CSCs), and epigenetic mechanisms that occur in solid CSCs. Potential applications of knowledge gained through this field and future prospects for cancer treatment also are discussed.

Citations

Dec 18, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mukesh VermaJohn P A Ioannidis
Feb 25, 2015·BMC Cancer·Sara Santos FrancoAndrás Dinnyes
Jul 25, 2021·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Wei WuHeike E Daldrup-Link

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