Epilepsia Partialis Continua as an Early Sign of Anti-Myelin Oligodendrocyte Glycoprotein Antibody-positive Encephalitis

Internal Medicine
Kazuto KatsuseHideji Hashida

Abstract

Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have been associated with steroid-responsive cortical encephalitis and comorbid generalized epilepsy. A 44-year-old woman developed repeated epilepsia partialis continua (EPC) without generalized seizures and was anti-MOG antibody-positive. Radiological abnormalities were detected in the bilateral medial frontoparietal cortices, but there were no cerebrospinal fluid abnormalities. She achieved remission with anti-epileptic drugs alone. However, encephalitis recurred four months later when pleocytosis appeared, and steroid therapy was effective. Altogether, EPC without typical cerebrospinal fluid features can be an early sign of anti-MOG antibody-positive encephalitis. Thus, patients with EPC of unknown etiology need to be screened for anti-MOG antibodies.

References

Jan 7, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·W L BellR A Radtke
Apr 2, 1999·Neurology·M G LansbergG W Albers
Jan 25, 2014·Lancet Neurology·Sophia VaradkarJ Helen Cross
Dec 29, 2016·Seizure : the Journal of the British Epilepsy Association·Rūta Mameniškienė, Peter Wolf
Jan 21, 2017·Neurology. Neuroimmunology and Neuroinflammation·Ryo OgawaKazuo Fujihara
Feb 18, 2017·Journal of Neurology, Neurosurgery, and Psychiatry·Juichi FujimoriKazuo Fujihara
Aug 3, 2018·Multiple Sclerosis and Related Disorders·Takamichi SugimotoTakemori Yamawaki
Aug 23, 2018·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L WangC Quan
Oct 23, 2018·Multiple Sclerosis and Related Disorders·Kazuto KatsuseTatsushi Toda
Nov 30, 2018·Rinshō shinkeigaku = Clinical neurology·Hiroshi AdachiYasufumi Kageyama

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BETA
pharmacotherapy

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