Epilepsia partialis continua in a patient with Behçet's disease

Clinical Neurology and Neurosurgery
Berrin AktekinKamil Karaali

Abstract

Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder of unknown aetiology. Neurological involvement is characterised either by primary parenchymal lesions or secondary to major vascular involvement. Seizures are rarely seen in BD and their occurrence can be related to seizure provoking factors or exacerbation of the disease. We experienced a case of neuro-BD presenting with subacutely developing mental and behavioral changes, followed by left dominant tetraparesis with bilateral pyramidal signs, fever and left hand focal motor seizures with elementery clonic motor signs which later evolved into right hand epilepsia partialis continua (EPC) of Kojevnikov. The seizures were very resistant to antiepileptic drugs and 8 months after neurological involvement the patient died. The EPC evolving after neurological involvement is associated with high mortality rate.

References

Jul 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·B WechslerP Godeau
Nov 1, 1996·Neuroradiology·S GerberC Marsault
Nov 5, 1999·Brain : a Journal of Neurology·D KiddP Rudge
Aug 16, 2002·Epilepsia·Ebru AykutluGülsen Akman-Demir

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Citations

Nov 6, 2010·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ruzica KravljanacLjubica Nikolic
May 7, 2013·Epilepsy Currents·Orrin DevinskySouhel Najjar
Jan 24, 2009·Lancet Neurology·Adnan Al-Araji, Desmond P Kidd

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