Epilepsy: A Spectrum Disorder

Cold Spring Harbor Perspectives in Medicine
Joseph Sirven

Abstract

Epilepsy, a disorder of unprovoked seizures is a multifaceted disease affecting individuals of all ages with a particular predilection for the very young and old. In addition to seizures, many patients often report cognitive and psychiatric problems associated with both the seizures themselves and its therapy. Epilepsy has numerous etiologies both idiopathic and acquired with a wide range of therapeutic responses. Despite numerous treatments available to control repetitive seizures including medications, diets, immunotherapy, surgery, and neuromodulatory devices, a large percentage of patients continue to suffer the consequences of uncontrolled seizures, which include psychosocial stigma and death.

Citations

Apr 8, 2016·Future Medicinal Chemistry·Giuseppina Di StefanoLuigi Fiume
Sep 4, 2019·Human & Experimental Toxicology·A B KaradumanS Ilgin
Sep 9, 2019·Experimental Neurobiology·Hyeok Hee KwonJoon Won Kang
Oct 7, 2019·Physiological Reports·Neela K CodaduR Ryley Parrish
Aug 26, 2020·Applied Neuropsychology. Child·Marwa ElhadyHeba A Elmalt
Mar 2, 2019·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Hyun-Jong Jang, Kyung-Ok Cho
Aug 6, 2020·Journal of Family Medicine and Primary Care·Ahmed Mohamed KabelAshwaq Shaman Almutairi
Jan 22, 2021·AJR. American Journal of Roentgenology·Maria R PonisioR Edward Hogan
Feb 18, 2020·Journal of Controlled Release : Official Journal of the Controlled Release Society·Mukta AgrawalAmit Alexander
Feb 24, 2021·Disease Models & Mechanisms·Grant F MarshallCatherine M Abbott
Mar 19, 2021·Journal of Experimental Pharmacology·Fakher RahimAlireza Malayeri
May 1, 2021·International Journal of Molecular Sciences·Laura DobladoMaria Monsalve
Jun 19, 2021·Progress in Neurobiology·Edward BeamerTobias Engel
Aug 14, 2021·Neuroscience and Biobehavioral Reviews·Esther PototskiyAlberto E Musto
Jul 9, 2021·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Kwabena F M OpuniCharles A Okai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Neurodiagnostic Journal
Joseph DrazkowskiWilliam O Tatum
Lancet
Cheryl AmorosoNatalie Grove
Transactions & Studies of the College of Physicians of Philadelphia
E Dwyer
© 2021 Meta ULC. All rights reserved