PMID: 9548226Apr 21, 1998Paper

Epilepsy, cerebral calcifications and clinical or subclinical coeliac disease. Course and follow up with gluten-free diet

Seizure : the Journal of the British Epilepsy Association
M A HernándezL Ortigosa

Abstract

We have studied four patients (three male, one female, age range 15-25 years) with epilepsy, bilateral occipital calcifications and latent coeliac disease (CD). The epilepsy started at mean age 7 years, in three cases there were partial seizures and in one case generalized seizure. Three cases had symptoms suggesting malabsorptive syndrome during infancy and one case was diagnosed CD before the onset of seizures. In all cases serologic markers of CD were found, especially antiendomisium antibody, and intestinal biopsy indicated several grades of atrophy. The electroencephalograph (EEG) findings pointed to focal abnormalities in three patients and generalized abnormalities in one patient. In all cases computer tomography (CT) showed bilateral, almost symmetrical occipital calcifications in the cortical subcortical layers. The enhanced CT were unremarkable and magnetic resonance images (MRI) were normal. After diagnosis of CD, all patients followed a gluten-free diet and in three patients a significant reduction in seizure frequency was observed. CD should be ruled out in all cases of epilepsy, cerebral calcifications of unexplained origin and malabsorption syndrome in infancy.

References

Jan 1, 1979·Child's Brain·Y Maki, A Semba
Mar 4, 1978·British Medical Journal·B T CooperW T Cooke
Jul 22, 1978·British Medical Journal·R W ChapmanC L Smith
May 1, 1976·Journal of Neurology, Neurosurgery, and Psychiatry·E BoltshauserR D Hoare
Jan 11, 1975·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·Y NumaguchiP J Sones
May 1, 1991·Acta paediatrica Scandinavica·A VenturaG Tommasini
Dec 12, 1991·The New England Journal of Medicine·J S Trier
Mar 1, 1991·Neurology·P CollinO Keyriläinen
Jun 1, 1987·Neurology·A B TalyN G Pratibha
Mar 1, 1985·European Journal of Pediatrics·L CorbeelR Eeckels
Jun 16, 1973·Lancet·E H Reynolds
Sep 1, 1974·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·P F Borns, L F Rancier
Mar 24, 1973·British Medical Journal·M MylotteB McNicholl
May 1, 1972·American Journal of Diseases of Children·M Andriola, J Stolfi
May 1, 1970·The American Journal of Medicine·P Lanzkowsky
Oct 1, 1984·Neuropediatrics·E Del GiudiceL C Pinto
Jan 1, 1982·Journal of the Neurological Sciences·H C KinneyJ P Grant
Jan 1, 1981·Gut·S MeyersH D Janowitz
Dec 1, 1993·Neuropediatrics·G TortorellaF Guzzetta
Oct 1, 1993·Acta Paediatrica·M R Tighe, P J Ciclitira
Aug 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·A MagauddaR Di Perri

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Citations

Aug 31, 2011·The Psychiatric Quarterly·Jessica R JacksonDeanna L Kelly
Jun 1, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·K RostamiR P Steegers-Theunissen
Mar 1, 2004·Journal of Clinical Neuromuscular Disease·Russell L ChinHoward W Sander
Jan 16, 2009·Revue neurologique·B El MoutawakilI Slassi
Mar 2, 2005·Brain & Development·Giuseppe Gobbi
Apr 12, 2005·Epilepsy & Behavior : E&B·Jouni RanuaJouko Isojärvi
Jun 21, 2015·Pediatric Neurology·Sedat IşıkayAlper Kanmaz
Oct 15, 2014·Schizophrenia Research·Jessica JacksonDeanna L Kelly
May 27, 2003·Diabetes Care·Michael Freemark, Lynne L Levitsky
Jan 30, 2014·Arquivos De Gastroenterologia·Camilo VieiraLuciana R Silva
Sep 13, 2019·Journal of Clinical Gastroenterology·Amelie TherrienJocelyn A Silvester
Sep 1, 2018·Journal of Neurology·Thomas JulianPanagiotis Zis
Jun 3, 2004·Pediatrics·Nathanel ZelnikAaron Lerner

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