Epilepsy surgery near or in eloquent cortex in children-Practice patterns and recommendations for minimizing and reporting deficits

Epilepsia
P JayakarInternational League Against Epilepsy

Abstract

We aimed to investigate the current practices guiding surgical resection strategies involving epileptogenic zones (EZs) near or in eloquent cortex (EC) at pediatric epilepsy surgery centers worldwide. A survey was conducted among 40 respondents from 33 pediatric epilepsy surgery centers worldwide on the weight assigned to diagnostic tests used to define the EZ and EC, how EC is viewed, and how surgeries are planned for foci near or in eloquent cortex. A descriptive analysis was performed that revealed considerable variation in the use of diagnostic tests and resective strategies toward EZ and EC. The wide variation in strategies may contribute to undesirable outcomes characterized by poor seizure control with added deficits and underscores the need to establish best practices in pediatric epilepsy surgery. The survey data were used to formulate a set of recommendations to help minimize deficits and to report them consistently.

References

Jul 22, 1998·Epilepsia·M DuchownyJ Bruce
Feb 9, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·T KralJ Schramm
Jan 2, 2010·Journal of Neurosurgery. Pediatrics·Edward F ChangNicholas M Barbaro
Mar 3, 2010·Journal of Neurosurgery. Pediatrics·Hideki OgiwaraTadanori Tomita
Jun 12, 2010·Epilepsy Research·Rani A SarkisImad M Najm
Sep 22, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jennifer N GelinasPaul Steinbok
Feb 3, 2011·Journal of Neurosurgery. Pediatrics·Ian G DorwardMatthew D Smyth
Oct 1, 2011·Epilepsia·Rani A SarkisWilliam E Bingaman
Feb 14, 2012·Journal of Neurosurgery·Nathan C RowlandEdward F Chang
Jan 1, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M von LeheM Simon
Feb 12, 2014·Epilepsia·Prasanna JayakarUNKNOWN Task Force for Paediatric Epilepsy Surgery, Commission for Paediatrics, and the Diagnostic Commission of the International L
Mar 19, 2014·Journal of Neurosurgery. Pediatrics·Philippe SchuchtJürgen Beck
May 24, 2014·Epileptic Disorders : International Epilepsy Journal with Videotape·Alexandra LiavaStefano Francione
Oct 6, 2014·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·James A BalogunJames T Rutka
Mar 17, 2015·Neuropsychologia·Olivier BoucherDang K Nguyen
Apr 10, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Alexander GroteDaniel Delev
Jul 29, 2015·Seizure : the Journal of the British Epilepsy Association·Jesper ReinholdsonKristina Malmgren
Aug 22, 2015·Epileptic Disorders : International Epilepsy Journal with Videotape·Ann HyslopPrasanna Jayakar
Feb 6, 2016·Acta neurologica Belgica·Lynn VermeulenWim Van Paesschen

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Citations

Nov 16, 2020·Epilepsia·William D GaillardUNKNOWN Task Force for Pediatric Epilepsy Surgery, Commission for Pediatrics, and the Surgical Commission of the International Leagu
Feb 22, 2021·Epilepsy & Behavior : E&B·Debopam SamantaM Scott Perry
Mar 30, 2021·Frontiers in Human Neuroscience·Olivier AronLouis Maillard
Apr 30, 2021·Neurosurgery·Kelly M PothNicholas M Boulis
Apr 18, 2020·Journal of Neurosurgery. Pediatrics·Alena JahodováPavel Kršek

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