Epilepsy surgery related to pediatric brain tumors: Miami Children's Hospital experience

Journal of Neurosurgery. Pediatrics
Aria FallahJohn Ragheb

Abstract

Pediatric brain tumors may be associated with medically intractable epilepsy for which surgery is indicated. The authors sought to evaluate the efficacy of epilepsy surgery for seizure control in pediatric patients with brain tumors. The authors performed a retrospective review of consecutive patients undergoing resective epilepsy surgery related to pediatric brain tumors at Miami Children's Hospital between June 1986 and June 2014. Time-to-event analysis for seizure recurrence was performed; an "event" was defined as any seizures that occurred following resective epilepsy surgery, not including seizures and auras in the 1st postoperative week. The authors analyzed several preoperative variables to determine their suitability to predict seizure recurrence following surgery. Eighty-four patients (47 males) with a mean age (± standard deviation) of 8.7 ± 5.5 years (range 0.5-21.6 years) were included. The study included 39 (46%) patients with gliomas, 20 (24%) with dysembryoplastic neuroepithelial tumors (DNETs), 14 (17%) with gangliogliomas, and 11 (13%) with other etiologies. Among the patients with gliomas, 18 were classified with low-grade glioma, 5 had oligodendroglioma, 6 had uncategorized astrocytoma, 3 had pilocytic astro...Continue Reading

References

Jul 1, 1993·American Journal of Medical Genetics·E Engel
Feb 1, 1997·Acta Orthopaedica Scandinavica·K A SiebenrockJ Poal-Manresa
Nov 21, 2007·Seizure : the Journal of the British Epilepsy Association·Jorge G BurneoRuben I Kuzniecky
Mar 3, 2010·Journal of Neurosurgery. Pediatrics·Hideki OgiwaraTadanori Tomita
Dec 12, 2012·Journal of Neurosurgery. Pediatrics·Micol BabiniFabio Calbucci
Dec 18, 2013·Epilepsia·Nitin Tandon, Yoshua Esquenazi
Jan 1, 2014·Brain : a Journal of Neurology·Johan PalludGilles Huberfeld

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Citations

Sep 24, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Tadanori TomitaTatiana Pundy
Sep 24, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Matthew T Brown, Frederick A Boop
Dec 16, 2017·Operative Neurosurgery·Luke D TomyczMark R Lee
Jun 1, 2019·Journal of Neurosurgery. Pediatrics·Ravindra AryaHansel M Greiner
Dec 5, 2017·Continuum : Lifelong Learning in Neurology·Mai Dang, Peter C Phillips
Aug 15, 2017·Epilepsia·Marco GiulioniUNKNOWN Commission for Epilepsy Surgery of the Italian League Against Epilepsy
Feb 12, 2021·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Gianfranco NataleGuido Bocci
Mar 13, 2021·Frontiers in Oncology·Diana Cristina GhindaGeorg Northoff
Jun 23, 2021·Physics in Medicine and Biology·Joseph Yuan-Mou YangFernando Calamante
Jul 13, 2021·Pediatric Clinics of North America·Luis E Bello-Espinosa, Greg Olavarria

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