Epilepsy

Current Biology : CB
Vikram R Rao, Daniel H Lowenstein

Abstract

Our cognitive abilities emerge from the coordinated activity of neurons in the brain. The average human brain contains 86 billion neurons that are richly interconnected through synapses, contact points for electrochemical communication. Patterns of synaptic connectivity create functional ensembles of neurons, called neural circuits, which mediate information processing in the brain. Neural circuits can be deconstructed further into basic motifs ('microcircuits') involving feedforward and feedback connections between different types of neurons that exert excitatory or inhibitory influence. At each level of neural circuitry, the opposing forces of excitation and inhibition are normally held in balance through a variety of homeostatic mechanisms.

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Citations

Apr 1, 2016·Expert Review of Neurotherapeutics·Aline P PansaniFulvio A Scorza
Oct 19, 2017·Neurosurgery·Maxime O BaudEdward F Chang
Oct 4, 2017·Endocrinology·Anil K AgarwalAbhimanyu Garg
Aug 13, 2020·Drug Delivery and Translational Research·Barnabas WilsonJosephine L Jenita
May 4, 2016·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Yi WangZhong Chen
Jul 1, 2020·CNS Neuroscience & Therapeutics·Li-Ying ChenCeng-Lin Xu
Apr 24, 2020·Tropical Medicine & International Health : TM & IH·Dylan R RiceFarrah J Mateen
Nov 21, 2021·Macromolecular Bioscience·Zerin M KhanScott S Verbridge

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