Epileptic attack, delirium, and a Creutzfeldt-Jakob-like syndrome during mianserin treatment

Neuropsychobiology
H KoponenP J Riekkinen

Abstract

Our report concerns 2 patients who developed delirium after an epileptic attack during mianserin treatment. In both cases the EEG showed a change with periodic sharp slow complexes similar to that seen in Creutzfeldt-Jakob disease. The symptoms subsided, however, and the EEG normalized after the antidepressant was discontinued, suggesting a noxious response to mianserin. If Creutzfeldt-Jakob-like changes in the EEG occur, the possible effect of antidepressant medication should be considered.

Citations

Jun 1, 1995·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·O BonneM Bloch
May 16, 2000·Auris, Nasus, Larynx·F GotoK Ogawa

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