Episodic Behavioural Regression in an 8-Year-Old Female: Sequelae of 22q11.2 Duplication Syndrome

Case Reports in Psychiatry
A Bahji, S Khalid-Khan

Abstract

22q11.2 duplication syndrome is a recently discovered genetic syndrome with unclear neuropsychiatric sequelae. While its connection to 22q11.2 deletion syndrome is actively investigated, case reports on the neuropsychiatric sequelae of affected individuals have been previously described, largely focusing on comorbid autism spectrum disorder. Here, we present the case of an 8-year-old female experiencing episodes of severe behavioural regression following medical illness. We analyze the case and relate it to the available literature and identify potential risk factors.

References

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Jul 12, 2005·American Journal of Medical Genetics. Part a·Marie-France PortnoïSandrine Marlin
Dec 21, 2005·Proceedings of the National Academy of Sciences of the United States of America·Noboru HiroiSoh Agatsuma
Apr 25, 2007·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Nahit Motavalli Mukaddes, Sabri Herguner
Dec 3, 2008·Developmental Medicine and Child Neurology·Gian Paolo RamelliGraziano Pescia
Jan 14, 2010·Case Reports in Medicine·Raymond A ClarkeDonald L Gilbert
Nov 13, 2013·Molecular Psychiatry·E ReesM J Owen
Feb 26, 2015·JAMA Psychiatry·Jacob A S VorstmanUNKNOWN International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

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Methods Mentioned

BETA
cognitive behavioural therapy

Related Concepts

Related Feeds

22q11 Deletion Syndrome

22q11.2 deletion syndrome, also known as DiGeorge syndrome, is a congenital disorder caused by a partial deletion of chromosome 22. Symptoms include heart defects, poor immune system function, a cleft palate, complications related to low levels of calcium in the blood, and delayed development. Discover the latest research on this disease here.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.

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