Episodic medication adherence in adolescents and young adults with perinatally acquired HIV: a within-participants approach

AIDS Care
Amy HawkinsAALPHI Steering Committee

Abstract

Due to the success of antiretroviral (ART) medications, young people living with perinatally acquired HIV (PHIV+) are now surviving into adolescence and young adulthood. Understanding factors influencing ART non-adherence in this group is important in developing effective adherence interventions. Most studies of ART adherence in HIV-positive populations assess differences in adherence levels and adherence predictors between participants, over a period of time (global adherence). Many individuals living with HIV, however, including PHIV+ young people, take medication inconsistently. To investigate this pattern of adherence, a within-participants design, focussing on specific episodes of adherence and non-adherence, is suitable (episodic adherence). A within-participants design was used with 29 PHIV+ young people (17 female, median age 17 years, range 14-22 years), enrolled in the UK Adolescents and Adults Living with Perinatal HIV cohort study. Participants were eligible if they could identify one dose of medication taken and one dose they had missed in the previous two months. For each of the two episodes (one adherent, one non-adherent), behavioural factors (whom they were with, location, routine, day, reminders) and psycholog...Continue Reading

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Citations

Jun 11, 2020·Clinical Drug Investigation·Luca ZomboriCaroline Foster
May 30, 2020·The Journal of the Association of Nurses in AIDS Care : JANAC·Ali JuddHannah Castro

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Methods Mentioned

BETA
Cognitive Behaviour Therapy

Software Mentioned

LifeWindows
Life Windows

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