Feb 4, 2015

Epistasis and Entropy

BioRxiv : the Preprint Server for Biology
Kristina Crona

Abstract

Epistasis is a key concept in the theory of adaptation. Indicators of epistasis are of interest for large system where systematic fitness measurements may not be possible. Some recent approaches depend on information theory. We show that considering shared entropy for pairs of loci can be misleading. The reason is that shared entropy does not imply epistasis for the pair. This observation holds true also in the absence of higher order epistasis.

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Mentioned in this Paper

Adaptation
Genetic Loci
Epistasis, Genetic

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