Epistaxis in anticoagulated patients: Fewer hospital admissions and shorter hospital stays on rivaroxaban compared to phenprocoumon

Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
Thomas C SauterAristomenis K Exadaktylos

Abstract

Treatment of epistaxis in patients on anticoagulants is challenging and associated with higher admission rates and longer hospital stays compared with patients without anticoagulation. However, there is little information about epistaxis in patients taking new direct oral anticoagulants such as rivaroxaban compared with patients on traditional vitamin K antagonists such as phenprocoumon. Retrospective cohort study. The study was conducted at the emergency department of the University Hospital Inselspital, Bern, Switzerland. All admissions to the emergency department of the University Hospital Inselspital, Bern, Switzerland from 1st July 2012 to 30th June 2016 with non-traumatic epistaxis on anticoagulant therapy with phenprocoumon or rivaroxaban were included. We compared clinical outcome parameters (admission rates, length of hospital stay and mortality) for both anticoagulant groups. We included 440 patients with epistaxis, 123 (28%) on rivaroxaban and 317 (72%) on phenprocoumon. Fewer hospital admissions and shorter hospital stays were found in patients under rivaroxaban (12 (10.4%) vs 57 (18.0%) patients, P=.033; 0.7±2.2 vs 1.5±3.7 days, P=.011) compared with phenprocoumon. Anterior epistaxis was more common in the rivaroxa...Continue Reading

References

May 1, 1995·Annals of Emergency Medicine·R A ViducichL W Gerson
Jul 1, 2005·Annals of Emergency Medicine·Daniel J PallinCarlos A Camargo
Sep 22, 2007·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·T W M WalkerG W McGarry
Feb 21, 2009·The New England Journal of Medicine·Rodney J Schlosser
Apr 22, 2015·The American Journal of Emergency Medicine·Mark D UtkewiczNadia I Awad
Jan 19, 2016·European Journal of Internal Medicine·Thomas C SauterAristomenis K Exadaktylos
Sep 7, 2016·Rhinology·K M Musgrave, J Powell

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Citations

Jan 19, 2018·Deutsches Ärzteblatt International·Rafael BeckAndreas Dietz
Jan 10, 2019·Pediatric Emergency Care·Thorsten SendMark Jakob
Sep 26, 2021·Irish Journal of Medical Science·Gavin DonaldsonRaghav C Dwivedi
Nov 24, 2021·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Petar StankovićThomas Wilhelm

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