EPITHELIAL DOWNGROWTH IN THE VITREOUS CAVITY AND ON THE RETINA IN ENUCLEATED SPECIMENS AND IN EYES WITH VISUAL POTENTIAL

Retina
Aleksandra V RachitskayaAudina M Berrocal

Abstract

To report clinical course and visual and anatomical outcomes of six eyes with histopathologically confirmed vitreous cavity and retina epithelial downgrowth. This is a retrospective 15-year review of archived pathologic slides and corresponding medical records of patients with vitreous cavity and retina epithelial downgrowth. Posterior segment epithelial downgrowth was defined as epithelial or goblet cells in the vitreous cavity or on the surface of the retina. Histopathologic diagnosis of epithelial downgrowth was made in 122 patients. Of those, 6 patients (5%) had vitreous cavity and retina epithelial downgrowth. Three patients developed blind painful eye, and epithelial downgrowth was identified in enucleated specimens. The other three eyes with visual potential presented with tractional retinal detachments. Epithelial downgrowth was identified in epiretinal membranes obtained during pars plana vitrectomy. The latter group had more previous surgeries (P = 0.03), and all had keratoprosthesis implantation as their last surgery. All three had pathologic specimens obtained at the time of the keratoprosthesis implantation; no anterior segment epithelial downgrowth was noted in two patients, and one patient had involvement of corn...Continue Reading

References

Nov 1, 1977·American Journal of Ophthalmology·J R Wolter
Jan 1, 1989·The British Journal of Ophthalmology·M J WeinerD M Albert
Nov 1, 1996·Journal of Cataract and Refractive Surgery·C H KarabatsasD L Easty
May 11, 2002·Archives of Ophthalmology·Subhransu RayDonald J D'Amico
Feb 14, 2003·Archives of Ophthalmology·Daniel A JewelewiczSteven M Litinsky
Nov 6, 2008·Clinical & Experimental Ophthalmology·Ralph C Eagle
Mar 16, 2011·Archives of Ophthalmology·Rebecca C StacyKathryn A Colby
Sep 15, 2011·Cornea·Kendall E DonaldsonRichard K Forster
Mar 1, 2012·Ophthalmology·Christopher J RudniskyUNKNOWN Boston Type 1 Keratoprosthesis Study Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
H Laqua, H E Völcker
Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
G AlexandrakisM Edward Wilson
© 2021 Meta ULC. All rights reserved