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Epithelial Vegfa specifies a distinct endothelial population in the mouse lung

bioRxiv

Nov 13, 2019

Lisandra Vila EllisJi-Chao Chen

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Abstract

The lung microvasculature is essential for gas exchange and commonly considered homogeneous. We show that VEGFA from the epithelium is required for a distinct endothelial cell (EC) population in the mouse lung. Vegfa is predominantly expressed by alveolar type 1 (AT1) cells and locally ...read more

Mentioned in this Paper

Carbonate Dehydratase
Epithelium
Gene Deletion
Lung
Laboratory mice
Pulmonary Gas Exchange
Retina
Endothelial Cells
Myofibroblasts
Pneumocytes
12
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Epithelial Vegfa specifies a distinct endothelial population in the mouse lung

bioRxiv

Nov 13, 2019

Lisandra Vila EllisJi-Chao Chen

DOI: 10.1101/840033

Abstract

The lung microvasculature is essential for gas exchange and commonly considered homogeneous. We show that VEGFA from the epithelium is required for a distinct endothelial cell (EC) population in the mouse lung. Vegfa is predominantly expressed by alveolar type 1 (AT1) cells and locally ...read more

Mentioned in this Paper

Carbonate Dehydratase
Epithelium
Gene Deletion
Lung
Laboratory mice
12

Similar Papers Found In These Feeds

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