PMID: 697128Jan 1, 1978Paper

Epithelioma (lobular) developing in a fibroadenoma: study of a case report and review of the literature

Annales d'anatomie pathologique
P Walter, C Kuentz

Abstract

Carcinoma developing in a fibroadenoma correspond, according to current criteria, to neoplasms inclused in fibroadenomas. One personal case and 42 others from the literature fall within this definition. These neoplasms, small in size, are asymptomatic. The average age of the patients at the time of discovery of the lesion was 44 years. Two thirds of these carcinomas were lobular in type (29 cases), the others being invasive (7 cases) or non-invasive (7 cases) galactophoric carcinomas. Lobular carcinomas in situ (25 cases) involved, at the same time, one or more fibroadenomas and the remaining breast tissue in 60% of surgical specimens (15 cases). Independent of the operative technique used (local excision, wide excision or radical mastectomy), the course of a lobular carcinoma in situ in a fibroadenoma is, in general, simple.

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