Epoxidation of alkenes by chloroperoxidase catalysis

Biochemical and Biophysical Research Communications
J GeigertS L Neidleman

Abstract

Chloroperoxidase from Caldariomyces fumago catalyzes the peroxidation of alkenes to epoxides. This enzyme is the only haloperoxidase of four tested capable of carrying out the reaction. These results further establish chloroperoxidase as a unique haloperoxidase, and adds this enzyme to the short list of other enzymes (e.g., cytochrome P-450) known to epoxidize alkenes.

Citations

May 25, 2010·Applied Microbiology and Biotechnology·Martin HofrichterTaina Lundell
Jan 1, 1995·Biochimie·F P GuengerichO Okazaki
Sep 1, 1989·FEMS Microbiology Reviews·S HartmansW Harder
Jul 3, 2007·Applied and Environmental Microbiology·Dau Hung AnhMartin Hofrichter
Jan 1, 1997·Annual Review of Microbiology·A Archelas, R Furstoss
Jul 20, 2012·Bioinorganic Chemistry and Applications·Francesco G Mutti
Jan 30, 1987·Biochemical and Biophysical Research Communications·T N LiuJ C Hunter-Cevera
Jan 1, 1988·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·S M MoerleinT F Budinger
May 27, 2017·Chemical Communications : Chem Comm·Jia Jia DongFrank Hollmann
Jan 1, 1990·Critical Reviews in Biochemistry and Molecular Biology·F P Guengerich
Sep 6, 1996·The Journal of Biological Chemistry·R D LibbyA K Phipps
Feb 6, 2021·Biotechnology Advances·Carmen ArandaAna Gutiérrez

Related Concepts

Pentenes
Chloride Peroxidase
Cytochrome P-450 Oxygenase
Hyphomycetes
Epoxy Compounds
Ethers, Cyclic
Alpha-Peroxidase
Lactoperoxidase
Chromatography, Gas-Liquid-Mass Spectrometry
Peroxidase

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, as well as fevers and skin rashes. Here is the latest research on this disease.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Trichotillomania

Trichotillomania is an impulse control disorder characterized by the recurrent pulling of one's hair resulting in noticeable hair loss. Here are the latest discoveries in this field.

DDX3X Syndrome

DDX3X syndrome is caused by a spontaneous mutation at conception that primarily affects females due to its location on the X-chromosome. DDX3X syndrome has been linked to intellectual disabilities, seizures, autism, low muscle tone, brain abnormalities, and slower physical developments. Here is the latest research.