PMID: 5279517Apr 1, 1971

Epsilon-(gamma glutamyl) lysine in fibrin: lack of crosslink formation in Factor 13 deficiency

Proceedings of the National Academy of Sciences of the United States of America
J J PisanoY Nagai

Abstract

Fibrin clots formed in normal plasma contained about 6 mol of epsilon-(gamma-glutamyl)lysine per mol of fibrin, whereas those formed in plasma from individuals with Factor XIII deficiency contained little or none of this crosslink (0.02-0.64 mol/mol of fibrin). Partial supplementation of the plasma with Factor XIII, at a single concentration tested, commensurately increased the number of crosslinks.

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Citations

Jan 1, 1984·Molecular and Cellular Biochemistry·M Griffin, J Wilson
Aug 1, 1975·British Journal of Haematology·J McDonagh, R P McDonagh
Jul 1, 1977·British Journal of Haematology·L V McIntire
May 1, 1980·Journal of Clinical Pathology·F Rodeghiero, T Barbui
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Dec 8, 1972·Annals of the New York Academy of Sciences·S I Chung
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Aug 21, 2018·Advanced Materials·Anna SorushanovaDimitrios I Zeugolis
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Jan 1, 1981·Annals of the New York Academy of Sciences·P J Gaffney

Related Concepts

Blood Coagulation Disorders
Factor XIII A-Chain
Antithrombin I
Glutamic Acids
Lysine Hydrochloride
Polypeptides

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