Epstein-Barr virus and Burkitt lymphoma

Postgraduate Medical Journal
G BradyP J Farrell

Abstract

Burkitt lymphoma (BL) is an aggressive B-cell malignancy with endemic, sporadic and immunodeficiency-associated variants. It has been known for many years that the fundamental transforming event in BL is the translocation of the MYC gene, and the events that bring about this translocation and those that allow cells to survive with the constitutive expression of MYC have been the subject of intense investigation. Epstein-Barr virus (EBV) infection, malaria, immunodeficiency and spontaneous, somatic mutation can all contribute to the origin and maintenance of this cancer and their mechanisms are the subject of this review.

References

Oct 16, 1975·Nature·B M Greenwood, R M Vick
Mar 1, 1992·Trends in Genetics : TIG·G C Prendergast, E B Ziff
Jun 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·G GaidanoR Dalla-Favera
Apr 15, 1985·International Journal of Cancer. Journal International Du Cancer·M RoweM A Epstein
Mar 15, 1986·International Journal of Cancer. Journal International Du Cancer·M RoweA B Rickinson
Jan 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·J SaridP Leder
Jun 1, 1972·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·U IversenS Kyalwasi
Jun 15, 1982·International Journal of Cancer. Journal International Du Cancer·J WielsT Tursz
Jun 15, 1983·International Journal of Cancer. Journal International Du Cancer·D J MossP F Heywood
Aug 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·K NishikuraC M Croce
Dec 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·W DunnickC Dery
Apr 15, 1984·Cancer·E SaribanI T Magrath
Jul 28, 1995·Biochimica Et Biophysica Acta·G Packham, J L Cleveland
Jul 15, 1994·Biochemical and Biophysical Research Communications·R MasoodP S Gill
Feb 28, 1998·The EMBO Journal·L O'ConnorD C Huang
Jul 8, 1998·Proceedings of the National Academy of Sciences of the United States of America·T KamijoC J Sherr
Mar 17, 1999·Molecular Cell·R SearsJ R Nevins
Oct 29, 1999·Genes & Development·C M EischenJ L Cleveland
Jan 5, 2000·Proceedings of the National Academy of Sciences of the United States of America·Y ShouW M Kuehl

❮ Previous
Next ❯

Citations

Jun 4, 2011·Nature Reviews. Rheumatology·Catarina Dias, David A Isenberg
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Zachary J KrausGail A Bishop
May 16, 2008·Journal of Virology·Walter LucchesiPaul J Farrell
Jan 23, 2009·Journal of Virology·Brandon W HensonPrashant Desai
Oct 19, 2010·Journal of Oncology·Jason M God, Azizul Haque
Dec 17, 2008·Hematology·Archibald S Perkins, Jonathan W Friedberg
Jul 8, 2009·Infectious Agents and Cancer·Brady BeltranJorge Castillo
Jun 14, 2013·Case Reports in Oncological Medicine·Carlos ZagaloPedro David Santos
Dec 14, 2011·Clinical & Developmental Immunology·Azim HossainAzizul Haque
Jun 21, 2020·Head and Neck Pathology·Yi-Chan LeeKai-Ping Chang
Feb 13, 2021·Medical Sciences : Open Access Journal·Krishna C ThandraPrashanth Rawla
Oct 24, 2012·Integrative Cancer Therapies·Malek A ZihlifSaid I Ismail
Mar 6, 2021·Frontiers in Microbiology·Ya-Chun Yang, Bill Sugden
Jul 10, 2020·Pharmaceuticals·Franz GeisslingerKarin Bartel
May 2, 2020·International Journal of Molecular Sciences·Maria Manuel AzevedoFátima Baltazar
Aug 4, 2015·Biomedicines·Godfred FutagbiBartholomew D Akanmori
Mar 14, 2020·Endocrine·Jacqueline Fátima Martins AlmeidaLaura Sterian Ward
Mar 30, 2010·British Journal of Haematology·Kay Klapproth, Thomas Wirth
Jun 18, 2017·Molecular Cancer Therapeutics·Lisa Giulino-RothEthel Cesarman
Jul 27, 2018·Clinical Medicine Insights. Oncology·Adeyi A AdogaChukwunonso J Mgbachi
Jul 15, 2017·International Journal of Cancer. Journal International Du Cancer·Anthony R Mawson, Suvankar Majumdar
Dec 31, 2011·Acta Microbiologica Et Immunologica Hungarica·Tatjana Vilibic-CavlekGordana Mlinaric-Galinovic
Jan 12, 2012·British Journal of Haematology·Joe B Harford
Dec 3, 2015·MBio·Hem Chandra JhaErle S Robertson
Feb 11, 2016·Pathogens·Hem Chandra JhaErle S Robertson
Oct 22, 2013·G3 : Genes - Genomes - Genetics·Jennifer HardeeMichael Snyder
Apr 20, 2016·Frontiers in Microbiology·Shaoni BhattacharjeeAbhik Saha
Mar 16, 2021·Frontiers in Immunology·Nicholas B BlackburnJoanne E Curran
Apr 6, 2021·Frontiers in Veterinary Science·Luca AresuLaura Marconato

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.

Related Papers

Nature Reviews. Microbiology
Rosemary RochfordAnn M Moormann
Scandinavian Journal of Immunology
N RastiMaria Teresa Bejarano
International Journal of Gastrointestinal Cancer
Ira A JacobsVida Vizgirda
© 2022 Meta ULC. All rights reserved