Epstein-Barr virus-associated intracranial myopericytoma in a child: case report and review of literature.

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Manilyn Ann C Hong, Ibet Marie Y Sih

Abstract

Myopericytomas are benign soft tissue tumors which are rarely found as intracranial masses. A review of SCOPUS and PubMed databases for case reports and case series was done for patients with intracranial myopericytomas. Data on demographics, clinical features, imaging, surgical management employed, and outcomes were collected. We found a total of 9 cases in the literature and we describe an additional case from our own experience. The mean age at presentation was 50.1 years (32-64 years), with a female predominance. Most tumors were in the posterior fossa and were multifocal in AIDS patients. The most common clinical manifestations were visual disturbances, headaches, and vomiting. An association with EBV was reported in two cases and was also found in our own case. Gross total excision and even subtotal excision were definitive therapies with no recurrences reported with a mean follow-up of 22.7 months. Our case is the first EBV-associated intracranial myopericytoma in a child. Intracranial myopericytomas are rare; some have an association with EBV and immunodeficient states. Surgery is the only necessary treatment and outcomes are generally favorable for these benign neoplasms.

References

Nov 12, 2005·Neuropathology and Applied Neurobiology·A RousseauJ Poirier
Jan 18, 2008·Neuropathology and Applied Neurobiology·J CalderaroF Gray
Aug 14, 2009·The American Journal of Surgical Pathology·Patrick P L LauJohn K C Chan
Mar 18, 2011·Human Pathology·Pratistadevi K RamdialPravikrishnan Moodley
Jan 13, 2012·Acta Cytologica·Pam MichelowLiron Pantanowitz
Sep 2, 2014·British Journal of Neurosurgery·Catherine H ZhangAndrew J Martin
May 2, 2015·World Neurosurgery·Markus HollingAstrid Jeibmann
Jul 1, 2016·Archives of Pathology & Laboratory Medicine·Jyoti Dekate, Runjan Chetty
Jan 26, 2018·BMJ Case Reports·Rui Caetano OliveiraOlinda Rebelo

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