PMID: 8586837Nov 1, 1995Paper

Epstein-Barr virus (EBV) DNA in saliva and EBV serology of HIV-1-infected persons with and without hairy leukoplakia

The Journal of Infection
E LuchtA Linde

Abstract

Secretion of Epstein-Barr virus (EBV) in saliva, as well as serum antibody titres against various EBV antigens, were analyzed in respect of (1) 15 HIV-1-infected patients with oral hairy leukoplakia proven to contain EBV by in situ hybridization, (2) 45 HIV-1 infected patients without hairy leukoplakia, (3) 10 HIV-1 infected patients treated with acyclovir or foscarnet and (4) 21 healthy controls. The numbers of CD4+ cells in the peripheral blood were also recorded. The HIV-1 infected patients were at various stages of HIV-1-associated disease. Excretion of EBV DNA in the saliva was determined by means of the polymerase chain reaction (PCR) while the amount of EBV DNA in positive samples was estimated by repeated titrations. The frequency of shedding of EBV DNA increased from 33% in healthy controls to 78% in asymptomatic HIV-1 infected persons, but did not increase significantly with progression of HIV-1-associated disease. The titres of EBV DNA in saliva correlated inversely and significantly with the number of CD4+ cells in the peripheral blood. All patients with hairy leukoplakia shed by EBV DNA in their saliva but the titres were not significantly higher than those of other HIV-1 infected persons. The serum titres of antib...Continue Reading

References

Mar 1, 1989·The Journal of Infectious Diseases·M A RahmanC R Rinaldo
Apr 1, 1989·Oral Surgery, Oral Medicine, and Oral Pathology·J S Greenspan, D Greenspan
May 23, 1986·MMWR. Morbidity and Mortality Weekly Report·UNKNOWN Centers for Disease Control (CDC)
Dec 1, 1987·Oral Surgery, Oral Medicine, and Oral Pathology·M SchiødtJ S Greenspan
Feb 1, 1993·Journal of Medical Virology·E LuchtA Heimdahl

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Citations

Dec 8, 2010·Periodontology 2000·Jørgen Slots, Henrik Slots
Dec 4, 2004·The Journal of Allergy and Clinical Immunology·Anna SidorchukAnnika Linde
Jul 16, 2010·Archives of Oral Biology·R A P M PereraC S P Tsang
Jan 17, 2002·Journal of Medical Virology·Karen Brengel-PesceJean-Marie Seigneurin
Apr 1, 1997·Journal of Medical Virology·K I FalkI Ernberg
Dec 15, 2000·Journal of Acquired Immune Deficiency Syndromes : JAIDS·J W Cohen StuartR J de Boer
Jun 23, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Isabelle C WidmerGieri Cathomas
May 8, 2008·Journal of Medical Virology·Elizabeth GriffinAnna Wald
Dec 22, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·J PittW Shearer
Feb 12, 2012·World Journal of Virology·Massimo De Paschale, Pierangelo Clerici
Oct 16, 2020·Journal of Applied Microbiology·B MiyaniI Xagoraraki

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