Equivalence randomized controlled trial of bioresorbable versus titanium miniplates in treatment of mandibular fracture: a pilot study

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Krushna BhattRavinder Mohan Pandey

Abstract

The present study was undertaken to test bioresorbable fixation versus titanium for equivalence in terms of clinical union and complications using the American Association of Oral and Maxillofacial Surgeons parameters of care. The study design was a randomized, controlled, equivalence trial. A total of 40 patients were enrolled and allocated to the titanium group and bioresorbable group using a computerized randomization table. All were plated using standard plating principles. In the bioresorbable group, 2 weeks of maxillomandibular fixation was also used. Evaluation of the study endpoint was done at 8 weeks postoperatively. For statistical analysis, the upper limit of the 95% confidence interval was calculated for failure to achieve the primary outcome variable and compared with the maximal clinically acceptable difference between the standard and test modalities in the failure to achieve clinical union (delta). Delta was predetermined as 2%. The other complications were tested for significance using Fisher's exact test. Of the 40 patients, 21 were in the titanium group and 19 were in the bioresorbable group, with 20 men and 1 woman in the titanium group and 18 men and 1 woman in the bioresorbable group. The mean age was 28.7...Continue Reading

References

Dec 1, 1991·International Journal of Oral and Maxillofacial Surgery·L RixA Punnia-Moorthy
Aug 1, 1991·The British Journal of Oral & Maxillofacial Surgery·J S Brown, K Jones
Dec 1, 1973·Journal of Maxillofacial Surgery·H P Freihofer, H Sailer
Sep 1, 1983·The British Journal of Oral Surgery·D E FrostK F Moos
Jul 1, 1996·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·E Ellis, L R Walker
Apr 1, 1996·The British Journal of Oral & Maxillofacial Surgery·T F Renton, D Wiesenfeld
Aug 26, 1998·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·R A Meaders, S M Sullivan
Jul 12, 2003·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Jennifer LamphierMalvin Janel
Dec 19, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Robert M LaughlinJohn N Kent
Apr 8, 2009·Oral and Maxillofacial Surgery Clinics of North America·Edward Ellis
Jul 21, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Burak BayramCenk Balcik

❮ Previous
Next ❯

Citations

Aug 26, 2014·Dental Traumatology : Official Publication of International Association for Dental Traumatology·Wei WuGeng-Lin Sun
Apr 7, 2015·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Ashok DongolAlok Sagtani
Oct 21, 2016·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Jop P VerweijJ P Richard van Merkesteyn
Nov 22, 2014·Plastic and Reconstructive Surgery·Brad T MorrowDonald R Mackay
Dec 31, 2015·The Journal of Craniofacial Surgery·Tae Sung Lee
Oct 9, 2019·Plastic and Reconstructive Surgery. Global Open·Yehuda ChocronSabrina Cugno
Jul 10, 2013·The Cochrane Database of Systematic Reviews·Mona NasserKamran Ali
May 5, 2017·The Journal of Clinical Endocrinology and Metabolism·Wolfgang HöglerNicola Crabtree
Jan 24, 2021·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Adity BansalAshu Seith Bhalla
Jan 6, 2021·Oral and Maxillofacial Surgery·Bianca Cristina Lopes da SilvaSaulo Gabriel Moreira Falci

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Cochrane Database of Systematic Reviews
Mojtaba DorriRichard Oliver
Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
Walid A GhanemKhalid Saad
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Hyo-Bin LeeJun-Sik Son
The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
Constantin A Landes, Alexander Ballon
© 2021 Meta ULC. All rights reserved