Equivalency of human menopausal gonadotropin and follicle-stimulating hormone stimulation after gonadotropin-releasing hormone agonist suppression

Fertility and Sterility
M C EdelsteinS J Muasher

Abstract

This study compares the use of human menopausal gonadotropin (hMG) versus follicle-stimulating hormone (FSH), after gonadotropin-releasing hormone agonist (GnRH-a) suppression for in vitro fertilization. Thirty-seven patients were randomized to ovarian stimulation with either hMG or pure FSH. The GnRH-a leuprolide acetate was administered to all patients beginning in the midluteal phase of the prior cycle and continuing until the day of human chorionic gonadotropin (hCG) administration. There were no significant differences between hMG and FSH cycles with regard to the day of hCG administration, mean peak estradiol levels, number of ampules of medication used, and number of oocytes aspirated, embryos transferred, or pregnancies. We conclude that there is no significant difference between hMG and FSH stimulation when used in conjunction with GnRH-a.

Citations

Dec 3, 2003·Annals of the New York Academy of Sciences·Dimitris LoutradisStylianos Michalas
Jul 24, 1998·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·S Campo, N Garcea
Nov 1, 1993·British Journal of Obstetrics and Gynaecology·P VandekerckhoveT W Harada
Apr 4, 1998·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·R AgrawalH S Jacobs
Aug 16, 2000·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·S ZafeiriouS Michalas
Oct 1, 1993·Journal of Assisted Reproduction and Genetics·B HedonC Humeau
Dec 14, 2002·Gynécologie, obstétrique & fertilité·R Fanchin
Jun 1, 1993·Baillière's Clinical Obstetrics and Gynaecology·J Rabinovici

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