Erbium: YAG laser trabecular ablation with a sapphire optical fiber

Experimental Eye Research
M L McHamN Wang


The purpose of the study was to evaluate the effect of erbium (Er): yttrium aluminum garnet (YAG) laser trabecular ablation with a sapphire optical fiber on outflow facility. After obtaining baseline outflow facility using a computerized differential pressure perfusion system, human cadaver eyes were subjected to Er: YAG laser trabecular ablation using a sapphire optical fiber. Single pulses at varying energy levels (10 to 20 mJ pulse-1) were applied in a nearly contiguous fashion over four clock hours of meshwork. Post-laser outflow facility was then determined utilizing the same perfusion system and histopathologic analysis performed. Of the ten eyes, nine were perfused to steady baseline facility. One eye was excluded from the study because of a leak in our system during the initial perfusion. The mean baseline facility was 0.283+/-0.08 microl min-1 mmHg-1. There was a significant increase in outflow facility after trabecular ablation, with a mean post-laser facility of 0.62+/-0.15 microl min-1 mmHg-1 (P=0.01). Eyes which received a sham treatment showed no increase or a minimal increase in facility. Histopathologic analysis revealed ablation into Schlemm's canal with some thermal damage to the outer wall at all energy level...Continue Reading


Feb 1, 1977·American Journal of Ophthalmology·M H Luntz, D G Livingston
Jan 1, 1991·Lasers in Surgery and Medicine·R A HillM W Berns
Jun 1, 1988·Ophthalmology·R H BrownD D Brown
Feb 1, 1987·Ophthalmology·S MelamedD L Epstein
Jan 1, 1987·Archives of Ophthalmology·R H BrownJ M Parel
Jan 1, 1985·Archives of Ophthalmology·S MelamedD L Epstein
Jun 1, 1985·Archives of Ophthalmology·A L Robin, I P Pollack
Jul 1, 1985·Ophthalmology·D L EpsteinR F Steinert
Jul 1, 1974·Archives of Ophthalmology·M M Krasnov
Nov 1, 1970·American Journal of Ophthalmology·A P Nesterov
Aug 1, 1993·Current Eye Research·C R EthierR Pirog
Jul 1, 1993·Ophthalmology·J S SchumanR Lytle
Feb 1, 1955·A.M.A. Archives of Ophthalmology·W M GRANT, R R TROTTER
Oct 1, 1958·A.M.A. Archives of Ophthalmology·W M GRANT
Jun 1, 1963·Archives of Ophthalmology·W M GRANT
Aug 1, 1955·A.M.A. Archives of Ophthalmology·W M GRANT

❮ Previous
Next ❯


Jun 28, 2012·Journal of Biomedical Optics·Thomas C HutchensNathaniel M Fried
Feb 3, 2004·Lasers in Surgery and Medicine·Charles A ChaneyNathaniel M Fried
Dec 18, 2013·The British Journal of Ophthalmology·Kevin KaplowitzNils A Loewen
Mar 4, 2005·Current Opinion in Ophthalmology·Huck A Holz, Michele C Lim
Dec 13, 2003·Journal of Cataract and Refractive Surgery·Nicolas FeltgenJens Funk
May 22, 2021·BMC Ophthalmology·Noa KapelushnikAlon Skaat
Sep 1, 2005·Experimental Eye Research·Sami ToyranDeepak P Edward

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
H HoeraufH Laqua
Lasers in Surgery and Medicine
Tomonori Watanabe, Yuji Matsuura
Lasers in Surgery and Medicine
J M Krauss, C Puliafito
© 2021 Meta ULC. All rights reserved