ERCP-related perforations: risk factors and management

Endoscopy
R EnnsJ Baillie

Abstract

Perforations during endoscopic retrograde cholangiopancreatography (ERCP) are rare, and the management of these perforations is variable, with some patients requiring immediate surgery and others only conservative management. We reviewed all ERCP-related perforations at our institution to determine: a) their incidence; b) clinical outcomes; c) which management approaches gave the best results; and d) which factors predict a perforation. All patients who underwent ERCP and suffered perforation were reviewed. To compare the length of hospital stay of the perforation group with that of patients suffering a different complication, patients who developed post-ERCP pancreatitis were also reviewed. To evaluate predictors of ERCP-related perforations, three groups were compared: group 1 (n = 49), normal ERCP/no complications; group 2 (n = 52), ERCP complicated by pancreatitis; and group 3 (n = 33), ERCP with perforation. Of 33 patients with confirmed ERCP-related perforations, only seven patients required surgical intervention. The overall length of hospital stay (6.5 +/- 3.5 days) was significantly longer (P = 0.003) than that of a random group of patients with the complication of post-ERCP pancreatitis (4.7 +/- 2.6 days). According t...Continue Reading

Citations

Oct 3, 2008·Surgical Endoscopy·Dimitrios V AvgerinosI Michael Leitman
Feb 3, 2007·Digestive Diseases and Sciences·E ParlakB Sahin
Jan 9, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ji Hun KimWook Hwan Kim
Oct 19, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Andreas PolydorouGeorgios Polymeneas
Jan 25, 2011·Current Gastroenterology Reports·Klaus Mergener
Nov 25, 2003·ANZ Journal of Surgery·Madhukumar PreethaKhee-Chee Soo
Sep 23, 2008·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Zhihai MaoMinhua Zheng
Sep 10, 2010·Diagnostic and Therapeutic Endoscopy·Fotios SampaziotisRichard J Dickinson
Jan 9, 2013·World Journal of Emergency Surgery : WJES·Massimo SartelliTomohisa Shoko
May 9, 2012·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Attila DubeczHubert J Stein
May 22, 2008·World Journal of Gastroenterology : WJG·Tae-Hoon LeeSun-Joo Kim
May 12, 2010·World Journal of Gastroenterology : WJG·Tae Hoon LeeSun-Joo Kim
Mar 15, 2013·JSLS : Journal of the Society of Laparoendoscopic Surgeons·Orhan AlimogluGurhan Bas
Nov 12, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Najib Al GhossainiPhilippe Bulois
Mar 21, 2012·Case Reports in Medicine·Missale SolomonRicardo Morgenstern
Sep 18, 2013·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Nalini M GudaAjay Kumar
Jan 10, 2014·Indian Journal of Anaesthesia·Santosh Kumar JaiswalNavdeep Singh Lamba
Aug 21, 2013·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Ashish Kumar JhaRagesh Babu Thandassery
Dec 24, 2013·Digestive Diseases and Sciences·Yoshikuni KawaguchiNobutaka Tanaka
Apr 3, 2012·Digestive Diseases and Sciences·Nicolien J Schepers, Henk R van Buuren
Dec 3, 2014·Gastrointestinal Endoscopy Clinics of North America·Christine BoumitriMichel Kahaleh
Dec 3, 2014·Gastrointestinal Endoscopy Clinics of North America·Jason N Rogart
Dec 3, 2014·Gastrointestinal Endoscopy Clinics of North America·Tarun Rustagi, Priya A Jamidar
Dec 9, 2010·Digestive Diseases and Sciences·John MenacherySameer Vankar
Jan 31, 2013·Digestive Diseases and Sciences·V SinghV Gupta
May 18, 2011·Hospital Practice·Geetha NallamothuDouglas G Adler
Aug 30, 2013·Expert Review of Gastroenterology & Hepatology·Toufic A Kachaamy, Douglas O Faigel
Apr 2, 2013·Gastrointestinal Endoscopy Clinics of North America·Bryan Balmadrid, Richard Kozarek
Jul 27, 2012·Gastrointestinal Endoscopy·Todd H BaronRichard A Kozarek
Jul 4, 2012·Gastrointestinal Endoscopy Clinics of North America·Martin L Freeman
Feb 22, 2012·Gastrointestinal Endoscopy·Michelle A AndersonJason A Dominitz
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Hao M WuFrancis R Sutherland
Sep 25, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jan N HilberathHolger K Eltzschig
Jan 21, 2009·Gastrointestinal Endoscopy·Francesco FerraraNicola D'Imperio
Oct 3, 2008·The Journal of Emergency Medicine·Francesca L Beaudoin, Jonathon H Valente
Jun 13, 2008·Gastrointestinal Endoscopy·Ian WallScott Tenner
Jun 26, 2008·Gastrointestinal Endoscopy·Patrick R Pfau
Dec 25, 2007·Gastrointestinal Endoscopy·Patrick R Pfau
Sep 15, 2012·Clinical Endoscopy·Michel Kahaleh, Martin Freeman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.