Erectile dysfunction in patients with liver disease related to chronic hepatitis B

Clinical and Molecular Hepatology
Min KimByung Seok Lee

Abstract

Despite sexual function making an important contribution to the quality of life, data on erectile function are relatively scant in patients with chronic liver disease. We evaluated the prevalence of and risk factors for erectile dysfunction (ED) in patients with liver disease related to hepatitis B, especially among those with chronic hepatitis B (CHB) or early-stage cirrhosis. In total, 69 patients (35 with CHB and 34 with hepatitis-B-related liver cirrhosis [HBV-LC]) aged 40-59 years were analyzed. Child-Pugh classes of A and B were present in 30 (88.2%) and 4 (11.8%) of the patients with HBV-LC, respectively. The erectile function of the patients was evaluated using the Korean version of IIEF-5. The prevalence of any ED was 24.6% for all patients, and 8.6% and 41.2% for those with CHB and HBV-LC, respectively (P=0.002). While there was only one (2.9%) CHB patient for each stage of ED, mild, moderate, and severe ED stages were seen in three (8.8%), one (2.9%), and ten (29.4%) of the HBV-LC patients, respectively. Multiple regression analysis identified the type of liver disease (P=0.010), hypertension (P=0.022), score on the Beck Depression Inventory (P =0.044), and the serum albumin level (P=0.014) as significant independent...Continue Reading

References

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Citations

Jan 26, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Rafael PaternostroArnulf Ferlitsch
Nov 24, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Shuet Fong NeongStephen E Congly
Sep 16, 2017·European Journal of Gastroenterology & Hepatology·Christos K TriantosKonstantinos Assimakopoulos
Apr 30, 2019·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Sara PhilonenkoMarika Rudler

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