Erectile Dysfunction is Common among Men with Acromegaly and is Associated with Morbidities Related to the Disease

The Journal of Sexual Medicine
Francesco LottiGiovanni Corona

Abstract

The prevalence of erectile dysfunction (ED) and its correlates in men with acromegaly has never been investigated. The aim of this study was to evaluate sexual function in men with acromegaly. Multicenter-based, retrospective analysis of a nonselected series of 57 acromegalic subjects (mean age: 52.7 ± 14.2 years) was performed. Acromegalic subjects reporting ED (n = 24) were compared with matched ED patients without acromegaly or pituitary disease (controls), selected from a cohort of more than 4,000 subjects enrolled in the Florence Sexual Medicine and Andrology Unit. Patients were interviewed using Structured Interview on Erectile Dysfunction (SIEDY) structured interview, a 13-item tool for the assessment of ED-related morbidities. Several clinical and biochemical parameters were taken. Penile color Doppler ultrasound (PCDU) was performed in a subgroup of 37 acromegalic subjects. ED was reported by 42.1% of acromegalic subjects. After adjusting for age and testosterone, acromegalic subjects with ED had a higher prevalence of hypertension and more often reported an impairment of sleep-related erections and a longer smoking habit. Accordingly, acromegaly-associated ED was characterized by a higher organic component and worse P...Continue Reading

References

Sep 1, 1966·The British Journal of Psychiatry : the Journal of Mental Science·S Crown, A H Crisp
Jul 7, 1993·JAMA : the Journal of the American Medical Association
Apr 27, 1999·European Journal of Endocrinology·C CaraniG Lombardi
Nov 4, 2000·The Journal of Urology·A J BeckerU Jonas
Sep 6, 2002·The Journal of Clinical Endocrinology and Metabolism·A ColaoG Lombardi
Feb 11, 2004·Endocrine Reviews·Annamaria ColaoGaetano Lombardi
Mar 19, 2004·Biology of Reproduction·Varadaraj ChandrashekarAndrzej Bartke
Apr 12, 2007·Psychotherapy and Psychosomatics·Giancarlo BalerciaEmmanuele A Jannini
May 29, 2009·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Jan 23, 2010·The Journal of Sexual Medicine·Dimitrios HatzichristouTara Symonds
Feb 23, 2010·The Journal of Clinical Endocrinology and Metabolism·Abdelouahid TajarUNKNOWN EMAS Group
Mar 18, 2010·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Jun 18, 2010·The New England Journal of Medicine·Frederick C W WuUNKNOWN EMAS Group
Jan 13, 2011·Arthritis Care & Research·Ylva HellandHanne Dagfinrud
Mar 24, 2011·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Oct 15, 2011·The Journal of Sexual Medicine·Giovanni CoronaFerdinando Fusco
May 19, 2012·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Sep 14, 2012·The Journal of Sexual Medicine·Jacques BuvatLuiz Otavio Torres
Sep 28, 2012·Journal of Endocrinological Investigation·M GaldieroA Colao
Oct 6, 2012·The Journal of Sexual Medicine·Valentina BoddiMario Maggi
Jan 10, 2013·Circulation. Cardiovascular Quality and Outcomes·Charalambos V VlachopoulosChristodoulos I Stefanadis
Sep 24, 2013·Best Practice & Research. Clinical Endocrinology & Metabolism·G CoronaM Maggi
Sep 24, 2013·Best Practice & Research. Clinical Endocrinology & Metabolism·Giovanni CoronaMario Maggi
Jan 8, 2014·Nature Reviews. Urology·Daniele SantiVincenzo Rochira
Jan 18, 2014·The Journal of Sexual Medicine·Giulia RastrelliMario Maggi
Apr 5, 2014·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Apr 8, 2014·Endocrine·Andrea SansoneAndrea Lenzi
Apr 10, 2014·Asian Journal of Andrology·Giovanni CoronaMario Maggi
Apr 30, 2014·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Dec 17, 2014·The Journal of Sexual Medicine·Roland PoppStephan Budweiser

❮ Previous
Next ❯

Citations

Mar 6, 2016·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Jan 23, 2017·The Journal of Sexual Medicine·Alexander EgebergJacob P Thyssen
Mar 14, 2018·Nature Reviews. Urology·Francesco Lotti, Mario Maggi
Mar 14, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Zhengyuan ChenZhaoyun Zhang
Feb 20, 2021·Journal of the Endocrine Society·Maria Laura MonzaniVincenzo Rochira
May 30, 2021·Journal of Endocrinological Investigation·M K YilmazP Kadioglu
Jul 3, 2021·Journal of Clinical Medicine·Gianmaria SalvioGiancarlo Balercia

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

© 2022 Meta ULC. All rights reserved