PMID: 8953428Nov 1, 1996Paper

Eremomastax speciosa: effects of leaf aqueous extract on ulcer formation and gastric secretion in rats

Journal of Ethnopharmacology
P V TanF J Ayafor

Abstract

The anti-ulcerogenic potential of the aqueous extract of Eremomastax speciosa leaves was investigated using two methods of ulcer induction: HCl/EtOH-induced ulceration and pylorus ligation. With both methods, the extract inhibited gastric ulceration in a dose-related manner. The highest oral dose tested (190 mg/kg) completely inhibited gastric ulceration and significantly reduced gastric acidity compared with the controls. Incubation of gastric juice with the plant extract (190 mg/kg) significantly reduced the acidity of the incubated gastric juice compared with the controls.

References

Feb 1, 1967·Experimental and Molecular Pathology·V CioliF Dordoni
Jun 1, 1971·European Journal of Pharmacology·G PrinoA Lietti
Mar 1, 1994·Journal of Ethnopharmacology·B K NoamesiJ Adotey

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Citations

Dec 13, 2000·Phytotherapy Research : PTR·F Borrelli, A A Izzo
Sep 2, 2000·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·P V TanE A Forcha
Dec 30, 2008·Journal of Ethnopharmacology·Bamidele V OwoyeleAyodele O Soladoye
Jan 17, 2012·Journal of Ethnopharmacology·Lakshmanan HariprasathRaaman Nanjian
Mar 22, 2013·PloS One·Kamal A KetulyMahmood A Abdulla
Jun 28, 2016·Inflammopharmacology·Souraya DomiatiHeba Abd El Razik
Jul 15, 2015·BMC Complementary and Alternative Medicine·Gilbert AteufackAlbert Kamanyi
Jul 19, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mehdi Sharifi-RadJavad Sharifi-Rad
Jul 31, 2007·Phytotherapy Research : PTR·G Kakub, M Gulfraz
Dec 5, 2020·BioMed Research International·Ifeanyi P OnyekaCyril Onyeka Ogbue

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