Abstract
This study examined serial changes in coronary flow velocity to elucidate the dynamic change of coronary circulation during coronary spasm. Twenty patients with variant angina and 27 control patients were studied. Coronary flow velocity was monitored using a Doppler guidewire following intracoronary ergonovine administration. In the control group, diastolic flow velocity either did not change or increased slightly in response to ergonovine. However, in patients with variant angina, 2 patterns of flow velocity alterations were observed. In the first pattern, flow initially increased and then suddenly decreased (16 of 20 patients). In the second pattern, flow gradually decreased (3 of 20 patients). In the remaining patient, the coronary flow alteration could not be detected because of branch spasm. When abnormally high flow velocity was defined as a 100% increase in flow after ergonovine administration within 1 minute, and abnormally low flow velocity was defined as a 50% decrease in flow to diagnose variant angina, sensitivities of 35%, 75%, and 85% were noted if flow was measured 1.0, 2.0, and 3.0 minutes after ergonovine administration, respectively. These abnormal flow velocities were observed before ischemic ST changes appea...Continue Reading
References
Feb 1, 1978·Circulation·D R RicciD C Harrison
Apr 1, 1978·The American Journal of Cardiology·F A HeuplerW C Sheldon
Jan 1, 1979·Circulation·P R CiprianoJ F Silverman
Jan 1, 1977·The American Journal of Cardiology·P R McLaughlinD C Harrison
Nov 1, 1977·Circulation·R C CurryC R Conti
Aug 1, 1976·Circulation·A MaseriA Pesola
Apr 1, 1975·Circulation·W G AustenB B Roe
May 1, 1992·Circulation·J W DoucetteJ Segal
Jun 1, 1992·Journal of the American College of Cardiology·K OkumuraE Morita
Jun 1, 1990·Circulation·A MaseriJ C Kaski
Sep 1, 1989·Circulation·E L JohnsonT A Ports
Sep 1, 1989·Journal of the American College of Cardiology·A HoshioH Mashiba
Oct 1, 1989·The American Journal of Cardiology·B P KimballH E Aldridge
Nov 1, 1987·Circulation·F KajiyaT Fujiwara
Jan 1, 1980·Catheterization and Cardiovascular Diagnosis·R A Chahine
Apr 1, 1980·Circulation·S ChierchiaA Maseri
Jul 1, 1980·Circulation·R L FeldmanC R Conti
Aug 1, 1980·The American Journal of Cardiology·F A Heupler
Aug 1, 1980·The American Journal of Cardiology·A Fester
Jan 1, 1980·Catheterization and Cardiovascular Diagnosis·A Fester
Citations
Jan 1, 2013·Case Reports in Cardiology·Michael RuisiPaul Schweitzer
Aug 20, 2008·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·R J WalhoutE M Buijs
Jun 9, 2005·International Journal of Cardiology·David AdlamAnthony Gershlick
Jan 27, 2016·Circulation·Laxmi S MehtaUNKNOWN American Heart Association Cardiovascular Disease in Women and Special Populations Committee of the Council on Clinical Card