Ericoside, a new antibacterial biflavonoid from Erica mannii (Ericaceae)

Fitoterapia
Gabin Thierry M BitchagnoPierre Tane

Abstract

A new dihydroflavonol-flavonol biflavonoid derivative, named ericoside was isolated from the ethanol extract of the whole plant of Erica mannii along with the known flavonoid, taxifolin 3-O-α-l-rhamnopyranoside; and two readily available sterols (sitosterol, sitosterol 3-O-β-d-glucopyranoside). The isolation was performed using chromatographic methods and the structure of purified molecules were elucidated using spectroscopic techniques (e.g. MS, NMR) and by comparison with literature data. The crude ethanol extract, ericoside, and taxifolin 3-O-α-l-rhamnopyranoside were tested against ten Gram-negative bacteria including multidrug resistant clinical isolates using a broth microdilution method. The crude ethanol extract showed no noteworthy activity. Of the purified compounds, ericoside displayed moderate activity against the resistant Escherichia coli AG100 with a MIC of 64μg/mL.

References

Nov 1, 1987·Journal of Ethnopharmacology·J L RíosA Villar
Mar 16, 2001·Phytochemistry·K LikhitwitayawuidT Phadungcharoen
May 27, 2003·Journal of Asian Natural Products Research·Pei-Cheng Zhang, Sui-Xu Xu
May 26, 2009·Journal of Ethnopharmacology·Jean De Dieu TamokouPierre Tane
Dec 18, 2010·International Journal of Antimicrobial Agents·V KueteJ-M Pagès
May 23, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bernadette Biloa MessiGerhard Bringmann

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Citations

Oct 23, 2018·Phytotherapy Research : PTR·Faegheh FarhadiMilad Iranshahy
Aug 31, 2019·Food & Function·Cristina CalejaIsabel C F R Ferreira
Oct 16, 2019·Natural Product Research·François DamenPierre Tane
Feb 28, 2020·Natural Product Reports·Lie-Feng MaZha-Jun Zhan
Nov 2, 2019·Natural Product Research·Brice Cedric K AtontsaPierre Tane
Nov 16, 2019·Natural Product Research·Gabin Thierry M BitchagnoTill Opatz
Jan 26, 2021·The Science of the Total Environment·José C J M D S Menezes, Vinícius R Campos
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Romeo D Tadjouate NagoAugustin Silvere Ngouela

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