Ero1 and redox homeostasis in the endoplasmic reticulum

Biochimica Et Biophysica Acta
Carolyn S Sevier, Chris A Kaiser

Abstract

Living cells must be able to respond to physiological and environmental fluctuations that threaten cell function and viability. A cellular event prone to disruption by a wide variety of internal and external perturbations is protein folding. To ensure protein folding can proceed under a range of conditions, the cell has evolved transcriptional, translational, and posttranslational signaling pathways to maintain folding homeostasis during cell stress. This review will focus on oxidative protein folding in the endoplasmic reticulum (ER) and will discuss the features of the main facilitator of biosynthetic disulfide bond formation, Ero1. Ero1 plays an essential role in setting the redox potential in the ER and regulation of Ero1 activity is central to maintain redox homeostasis and proper ER folding activity.

References

Nov 13, 1999·Nature Cell Biology·J W Cuozzo, C A Kaiser
Feb 15, 2000·The Journal of Biological Chemistry·A CabibboR Sitia
Apr 4, 2001·The EMBO Journal·M W BaderJ C Bardwell
Feb 21, 2002·The Journal of Clinical Investigation·Seiichi OyadomariMasataka Mori
Jan 14, 2003·Annual Review of Biochemistry·Hiroshi KadokuraJon Beckwith
May 20, 2003·European Journal of Biochemistry·Bernhard GessArmin Kurtz
Sep 19, 2003·Antioxidants & Redox Signaling·David P DixonAdam Benham
Feb 6, 2004·The Journal of Cell Biology·Benjamin P Tu, Jonathan S Weissman
Mar 3, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hideki EndohTetsuya Mitsudomi
May 27, 2004·The Journal of Biological Chemistry·Silvia Nerini MolteniRoberto Sitia
Jul 16, 2004·The Journal of Biological Chemistry·Seema Chakravarthi, Neil J Bulleid
Sep 8, 2004·Molecular Cell·Cole M HaynesAntony A Cooper
Oct 21, 2004·Biochemical Society Transactions·C E JessopN J Bulleid
Nov 18, 2004·Biochimica Et Biophysica Acta·Hitoshi Nakamoto, James C A Bardwell
Jul 14, 2005·The Journal of Biological Chemistry·Sanjika Dias-GunasekaraAdam M Benham
Jul 19, 2005·Biochemical and Biophysical Research Communications·Gábor NardaiPéter Csermely
Sep 13, 2005·Annual Review of Microbiology·Alan G Hinnebusch
Jan 13, 2006·Proceedings of the National Academy of Sciences of the United States of America·Einav GrossDeborah Fass
Feb 24, 2006·Molecular Biology of the Cell·Carolyn S Sevier, Chris A Kaiser
Oct 13, 2006·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Malin GustavssonHenrik Hagberg
Nov 1, 2006·Journal of Cell Science·Lloyd W Ruddock, Maurizio Molinari
Jan 9, 2007·Advances in Experimental Medicine and Biology·Yuichiro Shimizu, Linda M Hendershot
Apr 25, 2007·Molecular and Cellular Biology·Li QiangStephen R Farmer

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Citations

Jan 9, 2010·The Journal of Biological Chemistry·Yoshimi SugiuraKazuhiro Nagata
Sep 30, 2010·The Journal of Biological Chemistry·Alison BurkartSilvia Corvera
Jul 16, 2011·The Journal of Biological Chemistry·Kazutaka Araki, Kazuhiro Nagata
Feb 26, 2009·Antioxidants & Redox Signaling·Christine H Foyer, Graham Noctor
Nov 19, 2008·Antioxidants & Redox Signaling·Kristine Steen JensenJakob R Winther
Feb 27, 2009·Antioxidants & Redox Signaling·Yuichiro Shimizu, Linda M Hendershot
Jan 26, 2010·Antioxidants & Redox Signaling·Balázs EnyediMiklós Geiszt
Jan 22, 2010·Antioxidants & Redox Signaling·Andreas J Meyer, Tobias P Dick
Feb 9, 2010·Antioxidants & Redox Signaling·Vamsi K Kodali, Colin Thorpe
Feb 9, 2010·Antioxidants & Redox Signaling·Motti Hakim, Deborah Fass
May 22, 2010·Antioxidants & Redox Signaling·Timothy J Tavender, Neil J Bulleid
Jan 22, 2011·Antioxidants & Redox Signaling·Guoping Ren, James C A Bardwell
Dec 8, 2011·Antioxidants & Redox Signaling·Kazutaka Araki, Kenji Inaba
Nov 30, 2011·Antioxidants & Redox Signaling·Saikh Jaharul HaqueSailen Barik
Dec 19, 2012·Antioxidants & Redox Signaling·Alberto Bindoli, Maria Pia Rigobello
Feb 5, 2010·Molecular Biology of the Cell·Paul MooreBilly Tsai
Apr 22, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·King-Tung ChinDavid Ron
Oct 13, 2009·Diabetes, Obesity & Metabolism·D F SteinerG I Bell
Nov 5, 2010·Diabetes, Obesity & Metabolism·A Volchuk, D Ron
Mar 30, 2010·Proteome Science·Stefania AngelucciCarmine Di Ilio
Sep 27, 2013·PLoS Genetics·Kira M Glover-CutterT Keith Blackwell
Mar 21, 2012·PloS One·Vishal M ShindeMarina S Gorbatyuk
May 8, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Alessia Di NardoMustafa Sahin
Dec 15, 2010·International Journal of Molecular Sciences·José R F MarquesAndré Melo
Dec 29, 2013·Apoptosis : an International Journal on Programmed Cell Death·Irina HirschDavid Michael Ferrari
Oct 24, 2013·Protoplasma·András Szarka, Tamás Lőrincz
Aug 31, 2013·Reviews in Endocrine & Metabolic Disorders·Tsu-Shuen Tsao
Sep 24, 2013·Antioxidants & Redox Signaling·Paula Nunes, Nicolas Demaurex
Jan 29, 2013·Cellular and Molecular Life Sciences : CMLS·Neysan DonnellyAfshin Samali
Sep 4, 2015·Free Radical Research·Madia TrujilloRafael Radi
Mar 24, 2010·The Journal of Cell Biology·Carolyn S Sevier
Mar 16, 2016·Pharmacology Research & Perspectives·Fabienne Foufelle, Bernard Fromenty
Jul 14, 2010·FEBS Letters·Eva Margittai, Gábor Bánhegyi

❮ Previous
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