Erosive-abrasive tissue loss in dentine under simulated bulimic conditions

Archives of Oral Biology
Nadine SchlueterCarolina Ganss

Abstract

The eroded organic dentine matrix is remarkably resistant to mechanical impacts. Additional brushing abrasion of eroded dentine has only limited influence on tissue loss. Digestive enzymes (e.g., pepsin, trypsin) that can reach the oral cavity during reflux or vomiting can partially degrade the matrix. This degradation may have an influence on both the stability of the matrix against mechanical forces and the susceptibility of eroded dentine to combined chemo-mechanical impacts. Both were investigated in the present study. Dentine samples of four groups were cyclically demineralised (6×2 min/day, 9 days) with an HCl-pepsin-solution (pH 1.6, 1.5mg/ml pepsin) and treated with a trypsin-solution (6×10 min/day, 2000 BAEE units/ml) directly afterwards. One group served as control; specimens of three groups were additionally brushed (2×15s/day) directly after the first and last trypsin treatment with forces of 200g, 300g, and 400g. Loss of demineralised and mineralised tissue was determined profilometrically. Additionally, an SEM analysis was performed. Loss of mineralised tissue (μm, mean±SD) was: 135.7±10.9 (control), 165.2±30.8 (200g), 168.0±16.3 (300g), and 174.9±17.1 (400g). Tissue loss was increased significantly (p≤0.001) by b...Continue Reading

References

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Jul 9, 2009·European Journal of Oral Sciences·Carolina GanssNadine Schlueter
Mar 4, 2010·Archives of Oral Biology·Nadine SchlueterCarolina Ganss
Mar 5, 2010·Journal of Dental Research·M T KatoM A R Buzalaf

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Citations

Apr 8, 2014·Journal of Dentistry·Arzu Aykut-YetkinerAnnette Wiegand
Nov 27, 2018·PloS One·Mariana Dias ModaPaulo Henrique Dos Santos
Oct 1, 2020·Journal of Applied Oral Science : Revista FOB·Mariana Dias ModaTiciane Cestari Fagundes
Jan 10, 2019·Journal of Applied Oral Science : Revista FOB·Mariana Dias ModaPaulo Henrique Dos Santos
Oct 12, 2019·Microscopy Research and Technique·Koray SoygunMuharrem Cem Dogan
Mar 31, 2021·Journal of Applied Biomaterials & Functional Materials·Koray SoygunMuharrem Cem Dogan

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