Erratum

Journal of Cataract and Refractive Surgery

Abstract

…The systems were the Paracel/Vibex Xtra, comprising riboflavin 0.25% solution containing TRIS and ethylenediaminetetraacetic acid and an isotonic solution of riboflavin 0.25%, (Group 1) and the CXLO system (Group 2)…. The mean riboflavin fluorescence intensity grades in Group 2 (4 eyes) were 3.8, 4.8, and 4.8 at 10, 15, and 20 minutes, respectively. The mean grades in Group 1 (3 eyes) were 2.0, 2.3, and 2.0, respectively. The riboflavin distribution was uniform in Group 2 but not in Group 1. The mean riboflavin concentration by liquid chromatography and mass spectrometry was 27.0 μg/g stromal tissue in Group 2 and 6.7 μg/g in Group 1. A stromal riboflavin concentration theoretically adequate for CXL, 15 μg/g, was achieved in all eyes in Group 2 and no eyes in Group 1…. The CXLO system (Group 2) produced corneal riboflavin concentrations that were theoretically adequate for effective transepithelial CXL (≥15 μg/g), while the Paracel/Vibex Xtra system (Group 1) did not.

Citations

Jul 16, 2021·Therapeutic Advances in Ophthalmology·Eray AtalayNilgün Yıldırım

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