Get paper from

journal cover

Error-prone DNA polymerase and oxidative stress increase the incidences of A to G mutations in tumors

Oncotarget

Jul 11, 2017

Jiannan Lin, Tie-Liu Shi

Get paper from

Abstract

Mutational processes for A→G mutations in tumors are not well understood. To uncover the mutational mechanisms, we analyzed molecular profiles of more than 9,000 tumor samples from The Cancer Genome Atlas (TCGA). The present study found that error-prone DNA polymerases were involved in ...read more

Mentioned in this Paper

deoxy(thymidylyl-cytidylyl-guanylyl-adenylic acid)
Oxidative Stress
Gene Mutation
Study
Thyroid Neoplasm
Malignant Neoplasm of Kidney
DNA Polymerase N3
Oxidative Stress Analysis
Mutation Abnormality
Genome
Paper Details
References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Error-prone DNA polymerase and oxidative stress increase the incidences of A to G mutations in tumors

    Oncotarget

    Jul 11, 2017

    Jiannan Lin, Tie-Liu Shi

    PMID: 28582771

    DOI: 10.18632/oncotarget.13293

    Abstract

    Mutational processes for A→G mutations in tumors are not well understood. To uncover the mutational mechanisms, we analyzed molecular profiles of more than 9,000 tumor samples from The Cancer Genome Atlas (TCGA). The present study found that error-prone DNA polymerases were involved in ...read more

    Mentioned in this Paper

    deoxy(thymidylyl-cytidylyl-guanylyl-adenylic acid)
    Oxidative Stress
    Gene Mutation
    Study
    Thyroid Neoplasm
    Paper Details
    References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Get paper from

    Hi! We use cookies on this site for analytics purposes. Visit our cookie policy to learn more. By continuing to use our services or closing this banner, you consent to our use of cookies.

    /papers/error-prone-dna-polymerase-and-oxidative-stress/28582771