PMID: 6979755Apr 1, 1982Paper

Errors associated with single-scan determinations of regional cerebral blood flow by xenon enhanced CT

Physics in Medicine and Biology
W F GoodW H Kennedy

Abstract

Possible errors in the determination of xenon concentrations in arterial blood, and uncertainties in CT tissue enhancements during inhalation of xenon-oxygen mixtures, are used to assess errors in the determination of regional cerebral blood flow by the in vivo autoradiographic (single-scan) technique. The results of this study indicate that errors associated with the determination of xenon concentrations in arterial blood decrease rapidly as the time of scanning after the initiation of xenon inhalation is increased. Analysis of errors caused by statistical uncertainties in image enhancement indicate that time of scanning is optimal between 1.5 and 2.5 min for determination of fast flow, while errors in slow-flow determinations gradually decrease as the time of scanning increases.

References

Mar 1, 1978·Stroke; a Journal of Cerebral Circulation·B P DrayerE E Cook
May 11, 1975·Stroke; a Journal of Cerebral Circulation·W D ObristW E Wilkinson
Aug 1, 1980·AJR. American Journal of Roentgenology·J S MeyerS Nakajima
Jun 1, 1981·Journal of Computer Assisted Tomography·D GurJ Gray
Aug 1, 1981·Journal of Computer Assisted Tomography·H YonasE E Cook
Jun 1, 1980·The British Journal of Radiology·M R KellerL R Kirkland

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Citations

Mar 1, 1983·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·D GurW F Good
Nov 1, 1982·Stroke; a Journal of Cerebral Circulation·D GurE E Cook
Jan 29, 1993·Science·B E HendersonM C Pike
May 1, 1983·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics

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