Erythema multiforme photoinduced by statins

Photodermatology, Photoimmunology & Photomedicine
Laura Rodríguez-PazosJaime Toribio

Abstract

We report two cases of systemic photosensitivity induced by simvastatin and pravastatin that presented as photodistributed erythema multiforme. One of them occurred in a 75-year-old woman who had been suffering recurrent eruptions following sun exposures over a period of 12 years. The other patient was a 54-year-old man who had a 1-week history of pruritic lesions on the face and the hands. They had no history of herpes simplex virus infection. In both cases, the close temporal relationship between drug ingestion and onset of the conditions suggested statin-induced photosensitivity. The diagnosis was confirmed by the marked reduction of UVB-MED or both UVA and UVB-MED while taking the drug and its normalization after discontinuing the statin intake.

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Citations

Nov 1, 2011·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·P NenoffH-J Tietz
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Nov 19, 2011·Photodermatology, Photoimmunology & Photomedicine·Enrique Gutiérrez-GonzálezJaime Toribio
Jul 7, 2011·Photodermatology, Photoimmunology & Photomedicine·Laura Rodríguez-PazosJaime Toribio
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