Erythematotelangiectatic rosacea may be associated with a subclinical stage of demodicosis: a case-control study

The British Journal of Dermatology
F Forton, V De Maertelaer

Abstract

Facial densities of Demodex mites have been observed to be greater in patients with demodicosis and papulopustular rosacea than in healthy control patients. In patients with erythematotelangiectatic rosacea (ETR), this density has been observed to be similar to or greater than that of healthy controls. Erythema and telangiectasia, characteristics of ETR, are often observed among patients with pityriasis folliculorum, a discreet demodicosis, suggesting a possible link between these conditions. To compare the facial Demodex densities of patients with clinical ETR and patients with healthy skin, demodicosis, rosacea with papulopustules, and other facial dermatoses. In this retrospective study, we recorded Demodex densities measured using two consecutive standardized skin surface biopsies (SSSB1 and SSSB2) in 23 patients with ETR, 20 healthy control patients, 590 patients with demodicosis, 254 with rosacea with papulopustules and 180 with other facial dermatoses. Patients with ETR had higher Demodex densities (D cm-2 ) than did the healthy controls (mean ± SEM; SSSB1: 15·7 ± 6·3 vs. 1·8 ± 1·1 D cm-2 , P = 0·042; SSSB2: 38·0 ± 13·7 vs. 5·1 ± 2·1 D cm-2 , P = 0·026) and patients with other dermatoses (SSSB1: 0·4 ± 0·1 D cm-2 , P = 0·...Continue Reading

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Citations

Oct 3, 2019·The British Journal of Dermatology·J P Thyssen
Sep 9, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·F M N Forton, V De Maertelaer
Mar 20, 2020·The Journal of Dermatological Treatment·Jade G M LoggerRieke J B Driessen
May 2, 2020·Dermatitis : Contact, Atopic, Occupational, Drug·Joanna JarosPeter A Lio
Aug 13, 2020·International Journal of Dermatology·Laura D ChinRichard M Haber
Feb 23, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·Yuanzhuo WangQiuning Sun
Oct 14, 2021·Acta Dermato-venereologica·Martin SchallerJames Del Rosso

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