Erythrocyte sedimentation rate may help predict severity of obstructive sleep apnea

Sleep & Breathing = Schlaf & Atmung
Woo Hyun LeeJeong-Whun Kim

Abstract

Previous studies have shown a relationship between obstructive sleep apnea (OSA) and erythrocyte sedimentation rate (ESR), a representative marker for inflammation. We aimed to elucidate the possible association between elevated ESR and OSA severity. A total of 341 patients who visited a sleep center were retrospectively enrolled. Subjects underwent physical examination, overnight polysomnography (PSG), and blood sampling for ESR and high-sensitivity C-reactive protein (hs-CRP). We compared the ESR and hs-CRP level to OSA severity and measured their correlation with other PSG parameters. The ESR was significantly higher in patients with severe OSA (apnea-hypopnea index (AHI) ≥ 30) than those with simple snoring (AHI < 5; P = 0.016), mild OSA (5 ≤ AHI < 15; P = 0.010), and moderate OSA (15 ≤ AHI < 30; P = 0.042). Similarly, the hs-CRP level in patients with severe OSA was significantly higher than that in patients with simple snoring (P = 0.006) and mild OSA (P = 0.013). Multivariate analysis also showed that elevated ESR was associated with moderate and severe OSA (adjusted OR = 2.231 (P = 0.048) and 2.606 (P = 0.002), respectively) after adjusting for sex, age, body mass index, smoking, hypertension, diabetes mellitus, and hyp...Continue Reading

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Citations

Jan 13, 2016·Sleep & Breathing = Schlaf & Atmung·Tomoyuki Kawada
Jan 13, 2016·Sleep & Breathing = Schlaf & Atmung·Woo Hyun Lee, Jeong-Whun Kim
Sep 30, 2017·The Clinical Respiratory Journal·Volkan SozerHafize Uzun

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