Erythropoiesis and erythropoietin synthesis during aseptic acute inflammation

Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]
H M Leng, P I Folb

Abstract

Erythropoietin (Epo) production during acute inflammation induced by s. c. turpentine administration in experimental Long-Evans rats increased in response to reduced erythropoiesis. A close correlation was found between decreased haematocrit (Hct) and increased levels of tumour necrosis factor-alpha (TNF alpha) in this experimental system. The Epo response was not different between rats with acute inflammation and anaemia and control animals with a comparable degree of anaemia. It is concluded that Epo is not an acute phase reactant, and that the Epo response in acute experimental inflammation in rats is explained by the associated development of anaemia.

References

Jan 1, 1976·American Journal of Hematology·H Hara, M Ogawa
Feb 1, 1992·Clinical and Experimental Immunology·N C WoodG W Duff
Jun 14, 1990·The New England Journal of Medicine·C B MillerJ L Spivak
Nov 1, 1986·The Journal of Clinical Investigation·D H PerlmutterH R Colten
May 1, 1989·American Journal of Obstetrics and Gynecology·B F CrandallS T Perdue
Jan 1, 1989·Annals of the New York Academy of Sciences·G SchreiberJ Milland
Jun 2, 1989·JAMA : the Journal of the American Medical Association·J L SpivakT C Quinn
May 1, 1989·British Journal of Haematology·L WideG Birgegård
Mar 1, 1989·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·L L MoldawerA Cerami
Nov 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·M A GoldbergH F Bunn
Dec 1, 1987·The American Journal of Physiology·L L MoldawerK G Lundholm
Aug 1, 1971·British Journal of Haematology·G E Cartwright, G R Lee
Nov 1, 1983·Scandinavian Journal of Haematology·N E Hansen
Jan 1, 1982·Annals of the New York Academy of Sciences·I Kushner
Mar 23, 1957·Nature·L O JACOBSONL PLZAK

❮ Previous
Next ❯

Citations

May 26, 1999·Experimental Hematology·H M LengP I Folb
Sep 3, 1998·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·W Jelkmann
May 10, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·M C ThomasG Jerums
May 29, 2015·International Urology and Nephrology·M PappaK Katopodis
Oct 28, 2006·The British Journal of Radiology·V NuniaP K Goyal
Jan 1, 1998·European Journal of Haematology·A M el HassanW Jelkmann

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.