Erythropoietin processing in erythropoietic system and central nervous system.

Cytotechnology
M NagaoR Sasaki

Abstract

We describe possible functions of carbohydrates attached to growth factors and strategies to examine the functions, concentrating on erythropoietin, a major regulator of erythropoiesis. Erythropoietin in erythropoiesis functions as an endocrine hormone; it is produced by kidney cells and transferred into the circulation to hemopoietic sites. In the brain, erythropoietin acts on neurons in a paracrine fashion. Comparison of glycosylation has been made between kidney and brain erythropoietins.

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Citations

May 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·M SakanakaR Sasaki
Jul 20, 2021·Journal of Neurochemistry·Daniela C VittoriAlcira B Nesse

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