PMID: 11604583Oct 18, 2001Paper

Erythropoietin therapy versus red cell transfusion

Current Opinion in Hematology
L T Goodnough

Abstract

Erythropoietin therapy was approved for use as a blood conservation intervention beginning in 1989 for patients with medical anemia and in 1997 for surgical patients. The adoption of this strategy has been rapid in some settings (such as renal failure patients), progressive in others ( eg, cancer patients), and slow in others (surgery patients, for instance). At the same time, the risks of blood transfusion have declined substantially whereas the costs of blood transfusion have increased significantly. The evolution of new techniques such as acute normovolemic hemodilution (ANH) and the novel erythropoiesis-stimulating protein (NESP) bring new options to allogeneic blood transfusion. Erythropoietin therapy, with or without autologous blood procurement, is undergoing new scrutiny as an alternative to blood transfusion. This is not only because of traditional concerns regarding blood risks but because of new blood inventory and cost considerations.

References

Feb 11, 1999·The Journal of Bone and Joint Surgery. American Volume·B E BierbaumR B Welch
Feb 18, 1999·The New England Journal of Medicine·L T GoodnoughJ P AuBuchon
Apr 25, 2000·Transfusion·P ToyR B Weiskopf
Jun 1, 2000·The New England Journal of Medicine·H G Klein
Jun 22, 2000·Anesthesiology·D R Spahn, M Casutt
Jul 15, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C B BrezdenI F Tannock
Jul 29, 2000·Cancer Treatment Reviews·S MercadanteS Filosto
Aug 29, 2000·Transfusion·M L FinucaneC K Mertz
Aug 31, 2000·Critical Care Medicine·H L Corwin, S B Krantz
Sep 14, 2000·Proceedings of the National Academy of Sciences of the United States of America·M L BrinesA Cerami
Nov 9, 2000·Seminars in Hematology·S Soignet
Dec 5, 2000·Baillière's Best Practice & Research. Clinical Haematology·E C Vamvakas, A A Pineda
Apr 12, 2001·Transfusion Medicine·A B HutchinsonC D Hillyer
Apr 12, 2001·Transfusion Medicine·B G FeaganA Kirkley
Apr 20, 2001·British Journal of Cancer·J C Egrie, J K Browne

❮ Previous
Next ❯

Citations

Jul 9, 2008·World Journal of Urology·Tamer AboushwarebJames J Yoo
Jun 14, 2003·Orthopaedic Nursing·Beatrice B Turkoski
Sep 19, 2003·Current Medical Research and Opinion·Paul E StevensNorbert R Lameire
Dec 25, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Wolfgang C WinkelmayerJerry Avorn
May 22, 2004·Journal of Clinical Pharmacy and Therapeutics·R MacLarenR W Vandivier
Dec 11, 2003·The Veterinary Clinics of North America. Small Animal Practice·Sheila McCullough
Mar 1, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David P SteensmaCharles L Loprinzi
Jul 15, 2004·The Journal of Bone and Joint Surgery. American Volume·Jeffery L PiersonDonald R Earles
Mar 27, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jacques Lacroix, Baruch Toledano

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.