Escape of a plant virus from amplicon-mediated RNA silencing is associated with biotic or abiotic stress

The Plant Journal : for Cell and Molecular Biology
Michael TalianskyHugh Barker

Abstract

Strong RNA silencing was induced in plants transformed with an amplicon consisting of full-length cDNA of potato leafroll virus (PLRV) expressing green fluorescent protein (GFP), as shown by low levels of PLRV-GFP accumulation, lack of symptoms and accumulation of amplicon-specific short interfering RNAs (siRNAs). Inoculation of these plants with various viruses known to encode silencing suppressor proteins induced a striking synergistic effect leading to the enhanced accumulation of PLRV-GFP, suggesting that it had escaped from silencing. However, PLRV-GFP escape also occurred following inoculation with viruses that do not encode known silencing suppressors and treatment of silenced plants with biotic or abiotic stress agents. We propose that viruses can evade host RNA-silencing defences by a previously unrecognized mechanism that may be associated with a host response to some types of abiotic stress such as heat shock.

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Citations

Jun 10, 2011·Biochimica Et Biophysica Acta·Carmen Simón-Mateo, Juan Antonio García
Jan 30, 2010·The EMBO Journal·Nina V ChichkovaMichael Taliansky
May 19, 2009·Molecular Plant-microbe Interactions : MPMI·Mathew LewseyJohn P Carr
Sep 28, 2005·The Journal of General Virology·Sophie HauptMichael Taliansky
Aug 1, 2005·Plant Disease·Takashi KoboriYoshitaka Kosaka

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