PMID: 8444816Mar 1, 1993Paper

Escherichia coli SecB, SecA, and SecY proteins are required for expression and membrane insertion of the bacteriocin release protein, a small lipoprotein

Journal of Bacteriology
B OudegaJ Luirink

Abstract

The SecB, SecA, and SecY dependency of a small outer membrane lipoprotein in Escherichia coli, the bacteriocin release protein (BRP), was studied. The detrimental effect of BRP expression on the culture turbidity (quasi-lysis) was strongly reduced in the sec mutants. Immunoblotting and radioactive labeling experiments showed that the expression, membrane insertion, and processing of the BRP precursor are dependent on SecB, SecA, and SecY. Labeling experiments with hybrid BRP gene constructs revealed that the mature part of the BRP precursor and not its stable signal sequence is important for its SecB dependency.

References

Nov 24, 1979·Nucleic Acids Research·H C Birnboim, J Doly
Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·H TowbinJ Gordon
Jan 1, 1991·Annual Review of Biochemistry·W WicknerF U Hartl
Jan 1, 1990·Annual Review of Genetics·P J Schatz, J Beckwith
Jul 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·C A Kumamoto
Jan 1, 1987·Molecular & General Genetics : MGG·J LuirinkB Oudega
Jul 1, 1985·Journal of Bacteriology·C A Kumamoto, J Beckwith

❮ Previous
Next ❯

Citations

May 14, 2004·The Journal of Biological Chemistry·Linda FröderbergJan-Willem de Gier
Mar 10, 2011·Archives of Microbiology·Yuh-Ren ChenKin-Fu Chak
Dec 1, 1995·FEMS Microbiology Reviews·F J van der WalB Oudega
Mar 10, 2007·Microbiology and Molecular Biology Reviews : MMBR·Eric CascalesDanièle Cavard

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.