ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study

Journal of Cataract and Refractive Surgery
Peter BarryESCRS Endophthalmitis Study Group

Abstract

To report results in the European Society of Cataract & Refractive Surgeons (ESCRS) multicenter study of the prophylaxis of endophthalmitis after cataract surgery. Twenty-four ophthalmology units and eye clinics in Austria, Belgium, Germany, Italy, Poland, Portugal, Spain, Turkey, and the United Kingdom, with an administrative office in Ireland, coordinating center in England, and data management and statistical unit in Scotland. This partially masked randomized placebo-controlled multinational clinical study to evaluate prospectively the prophylactic effect of intracameral cefuroxime injection and/or perioperative levofloxacin eyedrops on the incidence of endophthalmitis after phacoemulsification cataract surgery began in September 2003 and was terminated early in January 2006. The study used random allocation of patients in a 2 x 2 factorial design. By the end of 2005, complete follow-up records had been received for 13 698 study patients. Such a clear beneficial effect from the use of intracameral cefuroxime had been observed that it was agreed it would be unethical to continue the study and to wait for the completion of all follow-up procedures before reporting this important result. If total reported cases of endophthalmit...Continue Reading

References

Jan 5, 2002·Ophthalmology·Thomas A CiullaSamuel Masket
May 31, 2002·Journal of Cataract and Refractive Surgery·Per G MontanMargareta Rylander
May 31, 2002·Journal of Cataract and Refractive Surgery·Per G MontanCharlotta Zetterström
May 11, 2005·Archives of Ophthalmology·Mehran TabanPeter J McDonnell
Jan 18, 2006·Journal of Cataract and Refractive Surgery·Magela GaratAintzane Alberdi
Apr 25, 2006·Journal of Cataract and Refractive Surgery·David V SealUNKNOWN ESCRS Endophthalmitis Study Group
Apr 25, 2006·Journal of Cataract and Refractive Surgery·Peter BarryUNKNOWN ESCRS Endophthalmitis Study Group

❮ Previous
Next ❯

Citations

Oct 27, 2007·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M D Becker, F Mackensen
Nov 18, 2011·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·W Behrens-Baumann
Apr 25, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Frank C SchlichtenbredeJost B Jonas
Jan 16, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tök Y OzlemOrnek Firdevs
Jun 6, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Y KeynanP Lagacé-Wiens
Jul 29, 2008·Japanese Journal of Ophthalmology·Yoshitsugu InoueUNKNOWN Preoperative Disinfection Study Group
Oct 20, 2012·Japanese Journal of Ophthalmology·Keiji InagakiKishiko Ohkoshi
Aug 29, 2009·Eye·M E Fernández-RubioC Cortés-Valdés
Jul 31, 2008·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Christopher N TaHerminia Mino De Kaspar
Jun 6, 2009·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Lingmin HeHerminia Miño de Kaspar
Feb 7, 2012·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Bengu Ekinci Koktekir, Bekir Sitki Aslan
Aug 29, 2012·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Regis P KowalskiFrancis S Mah
Dec 20, 2012·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Yoshitaka TasakaYuichi Ohashi
Mar 7, 2013·Surgical Infections·Dale W BratzlerUNKNOWN Society for Healthcare Epidemiology of America (SHEA)
Dec 20, 2007·Current Opinion in Ophthalmology·Francis Char DeCroos, Natalie A Afshari
Nov 15, 2011·Current Opinion in Ophthalmology·Charles Q Yu, Christopher N Ta
Oct 20, 2012·Current Opinion in Ophthalmology·Jayesh Vazirani, Sayan Basu
Sep 8, 2011·International Ophthalmology Clinics·Glenn YiuJames Chodosh
Jul 15, 2006·BMJ : British Medical Journal·David Allen, Abhay Vasavada
Dec 22, 2006·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Guy KleinmannRandall J Olson
May 14, 2010·Clinical Ophthalmology·Deepa R AnijeetClive O Peckar
Aug 20, 2008·Indian Journal of Ophthalmology·Renuka SrinivasanHarish Narasimha Belgode
Aug 20, 2008·Indian Journal of Ophthalmology·Aditya KelkarAarofil Shaikh
Feb 25, 2014·Journal français d'ophtalmologie·P LoriautM Labetoulle
Jan 15, 2014·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Takahiro UdaYuichi Ohashi
Jun 25, 2014·Journal of Cataract and Refractive Surgery·Chris H L LimIan C Francis
Dec 13, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M J KossH M de Kaspar
Oct 7, 2014·Ophthalmology·Edward J HollandJohn D Sheppard
Dec 3, 2014·Journal of Cataract and Refractive Surgery·Francis S MahUNKNOWN ASCRS Cornea Clinical Committee
Mar 31, 2009·Expert Opinion on Drug Delivery·Thirumurthy Velpandian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.