ESCRT complexes assembled and GLUEd

Structure
Sudharshan Eathiraj, David G Lambright

Abstract

The ESCRT-I, -II, and -III complexes act sequentially to sort monoubiquitinated transmembrane proteins into multivesicular bodies for targeted degradation in the lysosome. Two papers published in a recent issue of Cell provide insights into the structural organization and functional interactions of the ESCRT-I complex and ESCRT-II GLUE domain.

References

Aug 2, 2003·Current Opinion in Cell Biology·Camilla RaiborgHarald Stenmark
Aug 27, 2004·Nature·Aitor HierroJames H Hurley
Apr 18, 2006·Cell·Michael S KostelanskyJames H Hurley

❮ Previous
Next ❯

Citations

Mar 26, 2013·Trends in Cell Biology·John A SchielRytis Prekeris
Nov 26, 2011·Current Biology : CB·Julie A BrillAndrew Wilde

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autophagosome

An autophagosome is the formation of double-membrane vesicles that involve numerous proteins and cytoplasmic components. These double-membrane vesicles are then terminated at the lysosome where they are degraded. Discover the latest research on autophagosomes here.

Autophagosome

An autophagosome is the formation of double-membrane vesicles that involve numerous proteins and cytoplasmic components. These double-membrane vesicles are then terminated at the lysosome where they are degraded. Discover the latest research on autophagosomes here.

Related Papers

Developmental Cell
Thomas Slagsvold, Harald Stenmark
Biochemical Society Symposium
Maria Antonietta De Matteis, Giovanni D'Angelo
Journal of the American Chemical Society
G E Atilla-GokcumenU S Eggert
© 2022 Meta ULC. All rights reserved