Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever

Internal Medicine
Taro ShiogaHitoshi Niino

Abstract

A 51-year-old man visited our hospital with a main complaint of precordial pain, difficulty swallowing, and pyrexia. The patient was diagnosed with esophageal carcinosarcoma, based on the characteristic morphology noted on upper gastrointestinal endoscopy and histology tests, and he underwent surgical treatment. His preoperative blood granulocyte-colony stimulating factor (G-CSF) and interleukin-6 (IL-6) levels were high, and the surgical specimens were positive in both immunohistochemical tests; therefore, he was diagnosed with a G-CSF- and IL-6-producing tumor. When pyrexia is seen as a paraneoplastic symptom, it is important to consider and investigate the possibility of a cytokine-producing tumor.

References

Oct 1, 1988·Journal of Clinical Gastroenterology·K SasajimaK Takubo
Sep 1, 1973·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J KlasterskyL Debusscher
Feb 1, 1993·The American Journal of Medicine·A SuzukiH Imura
Aug 16, 2003·European Journal of Internal Medicine·Cristian BaicusAnda Baicus
Jul 22, 2014·Journal of Animal Physiology and Animal Nutrition·J M HavlinK Karges

❮ Previous
Next ❯

Methods Mentioned

BETA
SMA
biopsy

Related Concepts

Related Feeds

Carcinosarcoma

Carcinosarcoma is a malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. Discover the latest research on carcinosarcoma here.